Golbus J, McCune W J
J Rheumatol. 1987 Feb;14(1):129-34.
Giant cell arteritis (GCA) is a systemic vasculitis primarily affecting large and medium sized vessels. While the disease may present with blindness or other signs of extracranial vasculitis, symptoms referable to the peripheral nervous system are uncommon. We describe 2 patients with biopsy proven GCA who simultaneously developed peripheral neurologic lesions. The first developed a mononeuritis multiplex superimposed on a diffuse, primarily sensory and distal polyneuropathy; the second, a symmetric, primarily motor and distal polyneuropathy. We review the published experience of GCA with peripheral nerve involvement and discuss a possible pathophysiologic basis for its occurrence.
巨细胞动脉炎（GCA）是一种主要累及大中型血管的系统性血管炎。虽然该疾病可能表现为失明或其他颅外血管炎体征，但累及周围神经系统的症状并不常见。我们描述了2例经活检证实为GCA且同时出现周围神经病变的患者。第一例患者在弥漫性、主要为感觉性和远端性多发性神经病基础上并发多发性单神经炎；第二例患者则出现对称性、主要为运动性和远端性多发性神经病。我们回顾了已发表的GCA累及周围神经的经验，并讨论了其发生的可能病理生理基础。
