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基于文献的奥克良(Abelmoschus esculentus)的植物化学信息和药理学活性综述。

Phytochemical information and pharmacological activities of Okra (Abelmoschus esculentus): A literature-based review.

机构信息

Department for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Vietnam.

Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.

出版信息

Phytother Res. 2019 Jan;33(1):72-80. doi: 10.1002/ptr.6212. Epub 2018 Oct 22.

Abstract

This review aimed at summarizing phytochemical reports and biological activities of Abelmoschus esculentus L. from the database sources. For this, an up-to-date search was made in the PubMed, Science Direct, MedLine, Scopus, and Google Scholar. The findings suggest that A. esculentus contains various nutrients and important phytochemicals. It possesses a number of important biological activities, including antioxidant, anti-inflammatory and immunomodulatory, antibacterial, anticancer, antidiabetic, organ protective, and neuropharmacological activities. Moreover, the plant also has lipid-lowering, trypsin inhibitory, hemagglutinating, antiadhesive, and antifatigue activities. The fruit and seeds are well tolerated in humans and other animals. In conclusion, A. esculentus may be one of the best sources of pharmacologically active lead compounds. More research is necessary on its toxicogenetic effects in animals.

摘要

本综述旨在从数据库资源中总结蕹菜(Abelmoschus esculentus L.)的植物化学物质报告和生物活性。为此,在 PubMed、Science Direct、MedLine、Scopus 和 Google Scholar 中进行了最新的检索。研究结果表明,蕹菜含有各种营养物质和重要的植物化学物质。它具有多种重要的生物活性,包括抗氧化、抗炎和免疫调节、抗菌、抗癌、抗糖尿病、器官保护和神经药理学活性。此外,该植物还具有降血脂、胰蛋白酶抑制、血凝、抗粘连和抗疲劳活性。果实和种子在人类和其他动物中具有良好的耐受性。总之,蕹菜可能是具有药理活性的先导化合物的最佳来源之一。有必要对其在动物中的毒代动力学效应进行更多的研究。

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