Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Phytother Res. 2020 Sep;34(9):2192-2202. doi: 10.1002/ptr.6679. Epub 2020 Mar 27.
Metabolic syndrome is a disorder characterized by dyslipidemia, insulin resistance, abdominal fat, high blood pressure, hypertriglyceridemia, and diminished high density lipoprotein cholesterol. Okra (Abelmoschus esculentus L.), routinely called lady's finger, has belonged to the Malvaceae family. Okra is considered as a valuable crop due to the multiple functions of its leaves, buds, flowers, pods, stems, and seeds in traditional and modern medicines. Several bioactive components are presented in different parts of okra including polyphenolic compounds especially oligomeric catechins and flavonol derivatives such as quercetin. The antioxidant, anti-inflammatory, anticancer, immunomodulatory, gastroprotective, neuroprotective, lipid lowering, and antidiabetic effects of okra have been established. Although different in vivo and in vitro studies revealed that okra has an ability to overcome metabolic syndrome symptoms, the lack of clinical studies is notable. So, further clinical trials should be accomplished to confirm the role of okra in metabolic syndrome. The aims of this review are to gather different studies regarding the potential efficacy of okra in metabolic syndrome.
代谢综合征是一种以血脂异常、胰岛素抵抗、腹部脂肪、高血压、高三酰甘油血症和高密度脂蛋白胆固醇降低为特征的疾病。秋葵（Abelmoschus esculentus L.），通常称为羊角豆，属于锦葵科。由于其叶子、芽、花、荚、茎和种子在传统和现代医学中的多种功能，秋葵被认为是一种有价值的作物。秋葵的不同部位含有多种生物活性成分，包括多酚类化合物，特别是低聚儿茶素和类黄酮衍生物，如槲皮素。秋葵具有抗氧化、抗炎、抗癌、免疫调节、胃保护、神经保护、降血脂和降血糖作用。尽管不同的体内和体外研究表明秋葵具有克服代谢综合征症状的能力，但值得注意的是，缺乏临床研究。因此，应该进行进一步的临床试验来证实秋葵在代谢综合征中的作用。本综述的目的是收集关于秋葵在代谢综合征中的潜在功效的不同研究。
