Department of Clinical Nutrition, College of Applied Medical Sciences, University of Hail, Hail 2440, Saudi Arabia.
Department of Biology, College of Science, University of Hail, Hail 2440, Saudi Arabia.
Molecules. 2021 Jan 28;26(3):696. doi: 10.3390/molecules26030696.
Recently, there has been a paradigm shift from conventional therapies to relatively safer phytotherapies. This divergence is crucial for the management of various chronic diseases. Okra ( L.) is a popular vegetable crop with good nutritional significance, along with certain therapeutic values, which makes it a potential candidate in the use of a variety of nutraceuticals. Different parts of the okra fruit (mucilage, seed, and pods) contain certain important bioactive components, which confer its medicinal properties. The phytochemicals of okra have been studied for their potential therapeutic activities on various chronic diseases, such as type-2 diabetes, cardiovascular, and digestive diseases, as well as the antifatigue effect, liver detoxification, antibacterial, and chemo-preventive activities. Moreover, okra mucilage has been widely used in medicinal applications such as a plasma replacement or blood volume expanders. Overall, okra is considered to be an easily available, low-cost vegetable crop with various nutritional values and potential health benefits. Despite several reports about its therapeutic benefits and potential nutraceutical significance, there is a dearth of research on the pharmacokinetics and bioavailability of okra, which has hampered its widespread use in the nutraceutical industry. This review summarizes the available literature on the bioactive composition of okra and its potential nutraceutical significance. It will also provide a platform for further research on the pharmacokinetics and bioavailability of okra for its possible commercial production as a therapeutic agent against various chronic diseases.
最近,从传统疗法到相对更安全的植物疗法的范式转变已经发生。这种分歧对于各种慢性疾病的治疗至关重要。黄秋葵(L.)是一种受欢迎的蔬菜作物,具有良好的营养价值,同时具有一定的治疗价值,这使其成为各种营养保健品应用的潜在候选者。秋葵果实的不同部位(黏液、种子和豆荚)含有某些重要的生物活性成分,赋予其药用特性。秋葵的植物化学物质因其对各种慢性疾病的潜在治疗活性而受到研究,如 2 型糖尿病、心血管和消化系统疾病,以及抗疲劳作用、肝脏解毒、抗菌和化学预防作用。此外,秋葵黏液已广泛用于医学应用,如血浆替代物或血容量扩张剂。总的来说,秋葵被认为是一种易于获得、成本低的蔬菜作物,具有多种营养价值和潜在的健康益处。尽管有关于其治疗益处和潜在营养保健品意义的几篇报道,但秋葵的药代动力学和生物利用度的研究还很少,这阻碍了它在营养保健品行业的广泛应用。本综述总结了关于秋葵的生物活性成分及其潜在营养保健品意义的现有文献。它还将为进一步研究秋葵的药代动力学和生物利用度提供一个平台,以促进其作为治疗各种慢性疾病的治疗剂的可能商业化生产。