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视网膜的光损伤。

Light damage to the retina.

作者信息

McKechnie N M, Johnson N F

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Sep 28;203(3-4):283-92. doi: 10.1007/BF00409834.

DOI:10.1007/BF00409834
PMID:303476
Abstract

The retinae of anaesthetised Dutch rabbits were exposed to light of various known intensities for a period of 1 h. After this period the animals were sacrificed and tissue taken for investigation by light and electron microscopy. Changes were apparent in the visual cells and retinal pigment epithelium only at the highest intensities employed. The retinal pigment epithelium and the outer nuclear layer exhibited mild oedematous changes. The major components to be affected were the visual cell outer segments. Marked disruption and vesiculation were features of the cone outer segments, which was in distinct contrast to the focal damage observed in the rod outer segments.

摘要

将麻醉后的荷兰兔视网膜暴露于不同已知强度的光线下1小时。在此之后,处死动物并取组织进行光学显微镜和电子显微镜检查。仅在使用的最高强度下,视觉细胞和视网膜色素上皮出现明显变化。视网膜色素上皮和外核层呈现轻度水肿变化。受影响的主要成分是视觉细胞外节。明显的破坏和囊泡形成是视锥细胞外节的特征,这与在视杆细胞外节观察到的局灶性损伤形成鲜明对比。

相似文献

1
Light damage to the retina.视网膜的光损伤。
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Sep 28;203(3-4):283-92. doi: 10.1007/BF00409834.
2
Some aspects of radiant energy damage to the retina.辐射能对视网膜损害的某些方面。
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Nov 8;208(1-3):109-24. doi: 10.1007/BF00406986.
3
Recovery of the rabbit retina after light damage (preliminary observations).光损伤后兔视网膜的恢复(初步观察)
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1980;212(3-4):271-83. doi: 10.1007/BF00410521.
4
Morphology and time-course of defined photochemical lesions in the rabbit retina.兔视网膜特定光化学损伤的形态学及时间进程
Curr Eye Res. 1988 Sep;7(9):849-60. doi: 10.3109/02713688808997242.
5
The effects of laser photocoagulation in the retinal capillaries.激光光凝对视网膜毛细血管的作用。
Am J Ophthalmol. 1975 Oct;80(4):591-601. doi: 10.1016/0002-9394(75)90389-x.
6
Qualitative observations on the variation of light induced damage to the rabbit retina.
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1981;215(4):305-25. doi: 10.1007/BF00407669.
7
[Retinal reactions to intense light. I. Threshold lesions. Experimental, morphological and clinical studies of pathological and therapeutic effects of laser and white light].[视网膜对强光的反应。I. 阈值性病变。激光和白光的病理及治疗作用的实验、形态学和临床研究]
Adv Ophthalmol. 1975;31:159-232.
8
Potential retinal light damage from the use of therapeutic instruments.使用治疗仪器可能导致的视网膜光损伤。
Trans Ophthalmol Soc U K (1962). 1982 Apr;102 (Pt 1):140-6.
9
Traumatic retinopathy in primates. The explanation of commotio retinae.灵长类动物的创伤性视网膜病变。视网膜震荡的解释。
Arch Ophthalmol. 1978 Dec;96(12):2267-73. doi: 10.1001/archopht.1978.03910060563021.
10
Phototoxicity to the newborn primate retina.
Invest Ophthalmol Vis Sci. 1978 Feb;17(2):178-82.

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Orally active multi-functional antioxidants are neuroprotective in a rat model of light-induced retinal damage.口服活性多功能抗氧化剂对光诱导的视网膜损伤大鼠模型具有神经保护作用。
PLoS One. 2011;6(7):e21926. doi: 10.1371/journal.pone.0021926. Epub 2011 Jul 14.
2
Prediction of the effect of the choroidal circulation on the retinal temperature during illumination.光照期间脉络膜循环对视网膜温度影响的预测。
Bull Math Biol. 1981;43(2):233-8. doi: 10.1007/BF02459445.
3
Ocular hypothermia: anterior chamber perfusion.眼部低温疗法:前房灌注

本文引用的文献

1
The Anatomy and Histology of the Eye and Orbit of the Rabbit.兔子眼睛和眼眶的解剖学与组织学
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2
A theory of retinal burns.
Bull Math Biophys. 1962 Jun;24:115-28. doi: 10.1007/BF02477421.
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Retinal damage by light in rats.大鼠视网膜的光损伤
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Retinal damage by visible light. An electron microscopic study.可见光对视网膜的损伤。一项电子显微镜研究。
Arch Ophthalmol. 1968 Jan;79(1):69-78. doi: 10.1001/archopht.1968.03850040071019.
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The retinal pigment epithelium. IV. The damaging effects of radiant energy.
Arch Ophthalmol. 1968 Aug;80(2):265-79. doi: 10.1001/archopht.1968.00980050267022.
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Differential susceptibility of rod and cone cells to argon laser.视杆细胞和视锥细胞对氩激光的不同敏感性。
Arch Ophthalmol. 1973 Mar;89(3):228-34. doi: 10.1001/archopht.1973.01000040230014.
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Retinal repair after experimental xenon arc photocoagulation. I. A comparison between rhesus monkey and rabbit.
Am J Ophthalmol. 1973 Jan;75(1):32-52. doi: 10.1016/0002-9394(73)90651-x.
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Visual cells and the concept of renewal.
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Histopathology of ruby and argon laser lesions in monkey and human retina. A comparative study.猴和人视网膜红宝石激光与氩激光损伤的组织病理学:一项对比研究。
Br J Ophthalmol. 1975 Nov;59(11):610-30. doi: 10.1136/bjo.59.11.610.