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开始不活动后和循环外加脉冲后血压的变化。

Changes of blood pressure following initiation of physical inactivity and after external addition of pulses to circulation.

机构信息

Emeritus Director of Medical Services, Mt Sinai Medical Center of Greater Miami, Miami Beach, FL, USA.

University of Miami, Coral Gables, FL, USA.

出版信息

Eur J Appl Physiol. 2019 Jan;119(1):201-211. doi: 10.1007/s00421-018-4016-7. Epub 2018 Oct 22.

Abstract

PURPOSE

To determine whether an innovative, motorized, wellness device that effortlessly produces physical activity (JD) can mitigate the hypertensive effects of prolonged sitting or lying down.

METHODS

Twenty-two normotensive and hypertensive adults of both genders gave informed consent to participate in a randomized controlled crossover study of a passive simulated jogging device (JD) in both supine and seated postures. Each study participant was monitored with a continuous non-invasive arterial pressure monitoring device (CNAP) over 60 min. The initial 10 min served as baseline for each posture. The subjects were randomized to begin with either JD or SHAM control for 30 min, and monitoring was continued for an additional 10 min in one posture; three days later posture and order of JD or SHAM were changed.

RESULTS

In both seated and supine postures, SHAM was associated with a significant rise in blood pressure (BP) which was observed within 5-10 min; it continued to rise or remain elevated for over a 40-min observation period. In contrast, JD produced a significant decrease in both systolic and diastolic blood pressure in both postures. During recovery in seated posture JD decreased systolic and diastolic BP by - 8.1 and - 7.6 mmHg, respectively. In supine posture, a similar decrease in BP occurred.

CONCLUSIONS

There is rapid onset of increase in systolic and diastolic BP with physical inactivity in both supine and seated postures. Administration of JD significantly decreased BP in both postures. Further studies are needed to assess long-term effectiveness.

摘要

目的

确定一种创新的、电动的、促进健康的设备(JD)是否可以减轻长时间坐着或躺着对血压的影响。

方法

22 名血压正常和高血压的成年男女在知情同意的情况下参与了一项关于被动模拟慢跑设备(JD)在仰卧和坐姿两种姿势下的随机对照交叉研究。每个研究参与者都使用连续无创动脉压力监测设备(CNAP)监测 60 分钟。前 10 分钟是每个姿势的基线。研究对象被随机分为 JD 或 SHAM 对照组,每组 30 分钟,在一种姿势下继续监测 10 分钟;三天后改变 JD 或 SHAM 的姿势和顺序。

结果

在坐姿和仰卧位,SHAM 与血压显著升高相关,这一变化在 5-10 分钟内观察到;血压持续升高或在 40 分钟的观察期内保持升高。相比之下,JD 在两种姿势下都显著降低了收缩压和舒张压。在坐姿恢复期间,JD 分别降低收缩压和舒张压 -8.1 和 -7.6mmHg。在仰卧位,也出现了类似的血压下降。

结论

在仰卧位和坐姿中,不活动时血压的收缩压和舒张压会迅速升高。JD 的应用在两种姿势下都显著降低了血压。需要进一步研究以评估长期效果。

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