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10 岁时的焦虑障碍症状可预测青春期的饮食障碍症状和诊断。

Anxiety disorder symptoms at age 10 predict eating disorder symptoms and diagnoses in adolescence.

机构信息

Department of Psychiatry, University of Wisconsin - Madison, Madison, WI.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC.

出版信息

J Child Psychol Psychiatry. 2019 Jun;60(6):686-696. doi: 10.1111/jcpp.12984. Epub 2018 Oct 24.

Abstract

BACKGROUND

Cross-sectional associations between anxiety disorders and eating disorders (EDs) have been well documented; however, limited research has examined whether symptoms of anxiety disorders are prospectively associated with EDs. Identifying these longitudinal associations can aid in discerning relationships among eating and anxiety disorders and point toward a mechanistic understanding of developmental psychopathology. This study investigated the prospective associations between parent-reported anxiety in mid-childhood (age 10) and child-reported ED behaviors and disorders in adolescence (at ages 14 and 16 years) in a population-based sample.

METHODS

Participants were individuals enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based, prospective study of women and their children; 7,767 children whose parents provided data at age 10 were included in current analyses. An exploratory factor analysis identified latent anxiety factors at age 10, followed by a path analysis that evaluated associations between these factors and eating disorder symptoms and cognitions at age 14.

RESULTS

Parent-reported anxiety symptoms at age 10 yielded 5 factors: obsessive-compulsive disorder (OCD) symptoms related to symmetry and checking (Factor 1); OCD symptoms associated with aversion to dirt and germs (Factor 2); physical anxiety symptoms (Factor 3); worries (Factor 4); and social phobia symptoms (Factor 5). Factors 3 and 4 showed the most consistent, positive associations with a range of ED symptoms at age 14. Factor 3 predicted diagnosis of bulimia nervosa by age 16 (OR = 1.11, p = .007), whereas Factor 4 predicted diagnoses of anorexia nervosa (OR = 1.10, p = .01) and disordered eating by age 16 (OR = 1.08, p = .001).

CONCLUSIONS

Results indicate that symptoms of generalized anxiety in middle childhood may predict adolescent-onset ED symptoms and ED diagnoses.

摘要

背景

焦虑障碍与饮食障碍(ED)之间的横断面关联已有充分记录;然而,有限的研究检查了焦虑障碍的症状是否与 ED 具有前瞻性关联。确定这些纵向关联可以帮助辨别进食和焦虑障碍之间的关系,并为发展心理病理学提供机制理解。本研究在基于人群的样本中调查了儿童中期(10 岁)父母报告的焦虑症与青少年(14 岁和 16 岁)儿童报告的 ED 行为和障碍之间的前瞻性关联。

方法

参与者为参加阿冯纵向研究父母和孩子(ALSPAC)的个体,这是一项针对女性及其子女的基于人群的前瞻性研究;目前的分析包括 7767 名在 10 岁时父母提供数据的儿童。探索性因素分析确定了 10 岁时的潜在焦虑因素,然后进行路径分析,评估这些因素与 14 岁时饮食障碍症状和认知之间的关联。

结果

10 岁时父母报告的焦虑症状产生了 5 个因素:与对称和检查相关的强迫症(强迫症)症状(因素 1);与厌恶污垢和细菌相关的强迫症症状(因素 2);身体焦虑症状(因素 3);担忧(因素 4);和社交恐惧症症状(因素 5)。因素 3 和 4 与 14 岁时的一系列 ED 症状呈最一致、积极的关联。因素 3 预测到 16 岁时神经性贪食症的诊断(OR=1.11,p=0.007),而因素 4 预测到 16 岁时神经性厌食症(OR=1.10,p=0.01)和饮食障碍的诊断(OR=1.08,p=0.001)。

结论

结果表明,儿童中期广泛性焦虑症的症状可能预测青少年期 ED 症状和 ED 诊断。

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