Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.
Cancer Med. 2018 Dec;7(12):6331-6339. doi: 10.1002/cam4.1847. Epub 2018 Oct 24.
Physical activity has been shown to reduce the risk of breast cancer-specific mortality. Although factors associated with physical inactivity in breast cancer survivors have been studied, a detailed examination at the population level is still lacking.
We addressed this gap in 1236 women with a diagnosis of breast cancer from the 2016 Behavioral Risk Factor Surveillance System Cancer Survivorship module. Physical inactivity was defined as self-reported absence of leisure time physical activity. Factors examined in the multivariable logistic regression model included sociodemographic, behavioral factors, access to health care, health history, current cancer treatment, and pain from cancer or treatment.
Overall, older age (≥65 years: OR = 2.63, 95% CI: 1.25-5.55) and being underweight (BMI <18.5: OR = 6.11, 95% CI: 1.35-27.66), were identified as significant factors associated with physical inactivity. In models adjusting for sociodemographics (Model 1), and the prior plus behavioral factors (Model 2), pain from cancer or treatment was significantly associated with physical inactivity (Model 2: OR = 2.23, 95% CI: 1.16-4.28); however, after fully adjusting for all variables (Model 3), there was no longer evidence of a significant association between pain from cancer and physical activity in female survivors with breast cancer.
We identified demographic (older age) and physical (low BMI and pain) factors to be significantly associated with physical inactivity among breast cancer survivors. Future interventions to promote physical activity in breast cancer survivors could benefit by taking into account these factors to develop tailored recommendations for increasing activity.
体育活动已被证明可降低乳腺癌特异性死亡率。尽管已研究了与乳腺癌幸存者身体活动不足相关的因素,但在人群层面上仍缺乏详细的研究。
我们使用了来自 2016 年行为风险因素监测系统癌症幸存者模块的 1236 名乳腺癌诊断女性来填补这一空白。身体活动不足被定义为缺乏休闲时间的体育活动。多变量逻辑回归模型中检查的因素包括社会人口统计学、行为因素、获得医疗保健的机会、健康史、当前癌症治疗以及癌症或治疗引起的疼痛。
总体而言,年龄较大(≥65 岁:OR=2.63,95%CI:1.25-5.55)和体重不足(BMI<18.5:OR=6.11,95%CI:1.35-27.66)被确定为与身体活动不足相关的重要因素。在调整社会人口统计学因素的模型中(模型 1),以及在调整社会人口统计学和行为因素的模型中(模型 2),癌症或治疗引起的疼痛与身体活动不足显著相关(模型 2:OR=2.23,95%CI:1.16-4.28);然而,在充分调整所有变量后(模型 3),在患有乳腺癌的女性幸存者中,癌症引起的疼痛与身体活动之间不再存在显著关联。
我们确定了与乳腺癌幸存者身体活动不足相关的人口统计学(年龄较大)和身体(低 BMI 和疼痛)因素。未来促进乳腺癌幸存者身体活动的干预措施可以考虑这些因素,为增加活动制定有针对性的建议。