Manoli Romina, Chartaux-Danjou Laurence, Delecroix Helene, Daveluy Walter, Moroni Christine
a PSITEC Lab (EA 4072) , University of Lille , Villeneuve-d'Ascq , France.
b U.E.R.O.S. Lille , UGECAM Hauts-de-France , Lille , France.
Brain Inj. 2018;32(13-14):1684-1689. doi: 10.1080/02699052.2018.1539245. Epub 2018 Oct 25.
The aim of this study was to propose new measures to evaluate memory processes in patients with severe traumatic brain injury (TBI). In this purpose, we analyzed learning and consolidation processes depending on own patient's performance during a memory test.
One-week Free and Cued Selective Reminding Test - word version (1W-FCSRT-word), which special feature relies on a 30-min and a 1-week-delayed recall after encoding, was administered to a group of 43 patients with severe TBI (age range from 20 to 54 years) and a group of neurologically healthy volunteers matched for age and gender.
Patients performed worse than healthy volunteers for the learning score. Their forgetting percentage was above healthy volunteers' performance and difference between the two groups increased with the delay from the learning phase.
In patients with severe TBI, our results underlined an altered learning and an impairment of long-term consolidation. It is crucial to detect these deficits in the aim to highlight, with a better accuracy, these patients' memory complaints and to propose a better professional rehabilitation.
本研究旨在提出新的方法来评估重度创伤性脑损伤（TBI）患者的记忆过程。为此，我们根据患者在记忆测试中的自身表现分析学习和巩固过程。
对一组43例重度TBI患者（年龄范围20至54岁）和一组年龄及性别匹配的神经功能正常的志愿者进行了为期一周的自由和提示选择性回忆测试 - 单词版（1W-FCSRT-word），该测试的特点是在编码后有30分钟和1周延迟回忆。
患者在学习得分上比健康志愿者表现更差。他们的遗忘百分比高于健康志愿者，且两组之间的差异随着从学习阶段开始的延迟而增加。
在重度TBI患者中，我们的结果强调了学习改变和长期巩固受损。检测这些缺陷对于更准确地突出这些患者的记忆问题并提出更好的专业康复建议至关重要。
