Ng T P, Tsin T W, O'Kelly F J, Chan S L
Am Rev Respir Dis. 1987 Jun;135(6):1249-54. doi: 10.1164/arrd.1987.135.6.1249.
Respiratory symptoms and radiographic and lung function alterations were studied in a cross-sectional survey of gemstone workers in Hong Kong. The study population included a group of grinders, polishers, and buffers who were heavily exposed to dust (principally free silica) and a less exposed group of cutters and carvers. Among all 218 male workers who answered the respiratory questionnaire, heavily exposed workers reported significantly higher prevalence of respiratory symptoms suggestive of mucus hypersecretion. Radiological pneumoconiosis defined as opacities with profusion of 1/0 and above was found in 27% of 157 workers who accepted radiographic and lung function examination. Radiological opacities were significantly related to increasing years of employment in both groups of workers after taking into account age and smoking habits. Decline in forced vital capacity (FVC) was significantly related to increasing years of employment in both groups after allowing for the effects of age, height, and smoking. A modest decline in forced expiratory volume in one second (FEV1) was related to dust exposure which was of borderline statistical significance in polishers and buffers who smoked. Radiological pneumoconiosis did not have an independent effect on lung function when allowance was made for dust exposure.
在一项针对香港宝石工人的横断面调查中，对呼吸症状以及影像学和肺功能改变进行了研究。研究人群包括一组大量接触粉尘（主要是游离二氧化硅）的研磨工、抛光工和打磨工，以及一组接触粉尘较少的切割工和雕刻工。在所有218名回答了呼吸问卷的男性工人中，接触粉尘多的工人报告提示黏液分泌过多的呼吸症状患病率显著更高。在接受影像学和肺功能检查的157名工人中，27%的人被发现有影像学诊断的尘肺病，其定义为小阴影密集度为1/0及以上。在考虑年龄和吸烟习惯后，两组工人的影像学小阴影均与就业年限增加显著相关。在考虑年龄、身高和吸烟影响后，两组工人的用力肺活量（FVC）下降均与就业年限增加显著相关。一秒用力呼气容积（FEV1）有适度下降，这与粉尘接触有关，在吸烟的抛光工和打磨工中具有边缘统计学意义。在考虑粉尘接触因素后，影像学尘肺病对肺功能没有独立影响。
