Jing Nan, Li Haiyan, Yu Hao, Yan Zhiwei, Xu Qinghong, Wang Zhuo
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 15 Beisanhuan Donglu, Beijing 100029, P. R. China.
J Nanosci Nanotechnol. 2019 Feb 1;19(2):780-785. doi: 10.1166/jnn.2019.15750.
Silver plate was found to prevent spoilage of foods thousands year ago and Ag nanoparticle is known to have great antibacterial activity. In this study, Ag nanoparticles with low than 10 nm average diameter were prepared in the present of glucose. A hypothetical "molecular cage" was built by glucose molecules in solution to limit the chemical reaction in a tiny space and to control the size and morphology of Ag nanoparticles. A possible synthesis mechanism of Ag nanoparticles in confined space was proposed. and were used to investigate the antibacterial activity of the synthesized Ag nanoparticles. Compared with the Ag nanoparticles obtained by conventional chemical precipitation method, the Ag nanoparticles synthesized in our study have better antibacterial activities for both and in low concentrations.
数千年前人们就发现银盘可以防止食物变质，并且已知银纳米颗粒具有很强的抗菌活性。在本研究中，在葡萄糖存在的情况下制备了平均直径低于10 nm的银纳米颗粒。溶液中的葡萄糖分子构建了一个假设的“分子笼”，以将化学反应限制在一个微小的空间内，并控制银纳米颗粒的尺寸和形态。提出了在受限空间内银纳米颗粒可能的合成机制。并用于研究合成的银纳米颗粒的抗菌活性。与通过传统化学沉淀法获得的银纳米颗粒相比，我们研究中合成的银纳米颗粒在低浓度下对和都具有更好的抗菌活性。
