Research Center for Oceanography, Indonesian Institute of Sciences (LIPI), Jakarta 14430, Indonesia.
Research and Development Division of Marine Bio-Industry, Indonesian Institute of Sciences (LIPI), West Nusa Tenggara 83552, Indonesia.
Mar Drugs. 2018 Oct 23;16(11):399. doi: 10.3390/md16110399.
Marine algae have received great attention as natural photoprotective agents due to their unique and exclusive bioactive substances which have been acquired as an adaptation to the extreme marine environment combine with a range of physical parameters. These photoprotective substances include mycosporine-like amino acids (MAAs), sulfated polysaccharides, carotenoids, and polyphenols. Marine algal photoprotective substances exhibit a wide range of biological activities such as ultraviolet (UV) absorbing, antioxidant, matrix-metalloproteinase inhibitors, anti-aging, and immunomodulatory activities. Hence, such unique bioactive substances derived from marine algae have been regarded as having potential for use in skin care, cosmetics, and pharmaceutical products. In this context, this contribution aims at revealing bioactive substances found in marine algae, outlines their photoprotective potential, and provides an overview of developments of blue biotechnology to obtain photoprotective substances and their prospective applications.
海洋藻类由于其独特而独特的生物活性物质而备受关注,这些物质是为了适应极端海洋环境而获得的,同时还结合了一系列物理参数。这些光保护物质包括菌氨酸类似物(MAAs)、硫酸多糖、类胡萝卜素和多酚。海洋藻类光保护物质具有广泛的生物活性,如紫外线(UV)吸收、抗氧化、基质金属蛋白酶抑制剂、抗衰老和免疫调节活性。因此,这些独特的生物活性物质来源于海洋藻类,被认为具有在皮肤护理、化妆品和药物产品中的应用潜力。在这种情况下,本研究旨在揭示海洋藻类中的生物活性物质,概述其光保护潜力,并概述获得光保护物质的蓝色生物技术的发展及其潜在应用。