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眼眶放射治疗甲状腺眼病:病例报告及文献综述

Orbital radiotherapy for thyroid eye disease: case report with a review of the literature.

作者信息

Luu Andrew

机构信息

Torbay Hospital, Torbay & South Devon NHS Foundation Trust, Torquay, UK.

出版信息

BJR Case Rep. 2016 May 28;2(2):20150385. doi: 10.1259/bjrcr.20150385. eCollection 2016.

DOI:10.1259/bjrcr.20150385
PMID:30363645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6180866/
Abstract

Thyroid eye disease (TED) is a condition mainly associated with Graves' disease. We report a patient with moderate-tosevere TED who underwent a combination of intravenous and oral steroids and orbital radiotherapy that improved her visual acuity and colour vision drastically, and decreased upper lid oedema. We review the clinical features of this unusual condition, our patient's history and treatment, and the knowledge base from the current literature.

摘要

甲状腺眼病(TED)是一种主要与格雷夫斯病相关的病症。我们报告了一名患有中度至重度甲状腺眼病的患者,该患者接受了静脉注射和口服类固醇以及眼眶放射治疗的联合治疗,这极大地改善了她的视力和色觉,并减轻了上睑水肿。我们回顾了这种罕见病症的临床特征、我们患者的病史及治疗情况,以及当前文献中的知识库。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f01/6180866/0ce69a5c82e5/bjrcr.20150385.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f01/6180866/a17ee69b0aa3/bjrcr.20150385.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f01/6180866/0ce69a5c82e5/bjrcr.20150385.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f01/6180866/a17ee69b0aa3/bjrcr.20150385.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f01/6180866/0ce69a5c82e5/bjrcr.20150385.g002.jpg

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1
Orbital radiotherapy for thyroid eye disease: case report with a review of the literature.眼眶放射治疗甲状腺眼病:病例报告及文献综述
BJR Case Rep. 2016 May 28;2(2):20150385. doi: 10.1259/bjrcr.20150385. eCollection 2016.
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本文引用的文献

1
Orbital radiation therapy for Graves' ophthalmopathy: measuring clinical efficacy and impact.眼眶放射治疗Graves眼病:评估临床疗效及影响
Pract Radiat Oncol. 2014 Jul-Aug;4(4):233-9. doi: 10.1016/j.prro.2014.02.008. Epub 2014 Apr 3.
2
Comparative analysis of dosimetric parameters of three different radiation techniques for patients with Graves' ophthalmopathy treated with retro-orbital irradiation.三种不同放射技术治疗格雷夫斯眼病患者眶后放射的剂量学参数比较分析。
Radiat Oncol. 2012 Nov 26;7:199. doi: 10.1186/1748-717X-7-199.
3
Feasibility of tomotherapy for Graves' ophthalmopathy: Dosimetry comparison with conventional radiotherapy.
经颅磁刺激治疗 Graves 眼病的可行性:与常规放射治疗的剂量学比较。
Strahlenther Onkol. 2011 Sep;187(9):568-74. doi: 10.1007/s00066-011-2220-z. Epub 2011 Jun 28.
4
Selenium and the course of mild Graves' orbitopathy.硒与轻度格雷夫斯眼病的病程。
N Engl J Med. 2011 May 19;364(20):1920-31. doi: 10.1056/NEJMoa1012985.
5
Protracted hypofractionated radiotherapy for Graves' ophthalmopathy: a pilot study of clinical and radiologic response.Graves 眼病的迁延性低分割放射治疗:临床和影像学反应的初步研究。
Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):1285-91. doi: 10.1016/j.ijrobp.2010.09.015. Epub 2011 May 6.
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Graves' ophthalmopathy.格雷夫斯眼病。
N Engl J Med. 2010 Feb 25;362(8):726-38. doi: 10.1056/NEJMra0905750.
7
Orbital radiotherapy for thyroid-related orbitopathy.甲状腺相关性眼病的眼眶放射治疗。
Curr Opin Ophthalmol. 2004 Dec;15(6):479-82. doi: 10.1097/01.icu.0000144388.89867.03.
8
Somatostatin analogs: a new tool for the management of Graves' ophthalmopathy.生长抑素类似物:一种用于治疗Graves眼病的新工具。
J Endocrinol Invest. 2004 Mar;27(3):281-7. doi: 10.1007/BF03345278.
9
A randomized controlled trial of orbital radiotherapy versus sham irradiation in patients with mild Graves' ophthalmopathy.一项针对轻度格雷夫斯眼病患者的眼眶放射治疗与假照射的随机对照试验。
J Clin Endocrinol Metab. 2004 Jan;89(1):15-20. doi: 10.1210/jc.2003-030809.
10
Long-term safety of orbital radiotherapy for Graves' ophthalmopathy.格雷夫斯眼病眼眶放射治疗的长期安全性
J Clin Endocrinol Metab. 2003 Aug;88(8):3561-6. doi: 10.1210/jc.2003-030260.