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通过激光驱动的微点伽马射线源实现高能、高分辨率计算机断层扫描。

Towards high-energy, high-resolution computed tomography via a laser driven micro-spot gamma-ray source.

作者信息

Wu Y C, Zhu B, Li G, Zhang X H, Yu M H, Dong K G, Zhang T K, Yang Y, Bi B, Yang J, Yan Y H, Tan F, Fan W, Lu F, Wang S Y, Zhao Z Q, Zhou W M, Cao L F, Gu Y Q

机构信息

Science and Technology on Plasma Physics Laboratory, Research Center of Laser Fusion, CAEP, Mianyang, Sichuan, 621900, China.

IFSA Collaborative Innovation Center, Shanghai Jiao Tong University, Shanghai, 200240, China.

出版信息

Sci Rep. 2018 Oct 26;8(1):15888. doi: 10.1038/s41598-018-33844-7.

DOI:10.1038/s41598-018-33844-7
PMID:30367090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6203838/
Abstract

Computed Tomography (CT) is a powerful method for non-destructive testing (NDT) and metrology awakes with expanding application fields. To improve the spatial resolution of high energy CT, a micro-spot gamma-ray source based on bremsstrahlung from a laser wakefield accelerator was developed. A high energy CT using the source was performed, which shows that the resolution of reconstruction can reach 100 μm at 10% contrast. Our proof-of-principle demonstration indicates that laser driven micro-spot gamma-ray sources provide a prospective way to increase the spatial resolution and toward to high energy micro CT. Due to the advantage in spatial resolution, laser based high energy CT represents a large potential for many NDT applications.

摘要

计算机断层扫描(CT)是一种强大的无损检测(NDT)方法,随着应用领域的不断扩大而受到关注。为了提高高能CT的空间分辨率,研制了一种基于激光尾场加速器轫致辐射的微焦点伽马射线源。利用该源进行了高能CT实验,结果表明在10%对比度下重建分辨率可达100μm。我们的原理验证表明,激光驱动的微焦点伽马射线源为提高空间分辨率和实现高能微型CT提供了一种有前景的方法。由于在空间分辨率方面的优势,基于激光的高能CT在许多无损检测应用中具有巨大潜力。

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High-resolution μCT of a mouse embryo using a compact laser-driven X-ray betatron source.使用紧凑型激光驱动 X 射线电子感应加速器源对小鼠胚胎进行高分辨率 μCT 成像。
Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6335-6340. doi: 10.1073/pnas.1802314115. Epub 2018 Jun 5.
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Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone.
激光尾场加速器作为用于人体骨骼三维医学成像的硬X射线源。
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