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新生儿听力筛查方案及其结果:系统评价。

Newborn hearing screening protocols and their outcomes: A systematic review.

机构信息

University of the Witwatersrand, South Africa.

University of the Witwatersrand, South Africa.

出版信息

Int J Pediatr Otorhinolaryngol. 2018 Dec;115:104-109. doi: 10.1016/j.ijporl.2018.09.026. Epub 2018 Sep 25.

Abstract

OBJECTIVE

To conduct a review of the most current research in objective measures used within newborn hearing screening protocols with the aim of exploring the actual protocols in terms of the types of measures used and their frequency of use within a protocol, as well as their outcomes in terms of sensitivity, specificity, false positives, and false negatives in different countries worldwide.

METHODS

A systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Electronic databases such as PubMed, Google Scholar and Science Direct were used for the literature search. A total of 422 articles were identified, of which only 15 formed part of the current study. The 15 articles that met the study's criteria were reviewed. Pertinent data and findings from the review were tabulated and qualitatively analysed under the following headings: country; objective screening and/or diagnostic measures; details of screening protocol; results (including false positive and negative findings, sensitivity and/or specificity), conclusion and/or recommendations. These tabulated findings were then discussed with conclusions and recommendations offered.

RESULTS

Findings reported in this paper are based on a qualitative rather than a quantitative analysis of the reviewed data. Generally, findings in this review revealed firstly, that there is a lack of uniformity in protocols adopted within newborn hearing screening. Secondly, many of the screening protocols reviewed consist of two or more tiers or stages, with transient evoked otoacoustic emissions (TEOAEs) and automated auditory brainstem response (AABR) being most commonly used. Thirdly, DPOAEs appear to be less commonly used when compared to TEOAEs. Lastly, a question around routine inclusion of AABR as part of the NHS protocol remains inconclusively answered.

CONCLUSIONS

There is sufficient evidence to suggest that the inclusion of AABR within a NHS programme is effective in achieving better hearing screening outcomes. The use of AABR in combination with OAEs within a test-battery approach or cross-check principle to screening is appropriate, but the inclusion of AABR to facilitate appropriate referral for diagnostic assessment needs to be systematically studied.

摘要

目的

对当前用于新生儿听力筛查方案的客观测量方法的最新研究进行综述,旨在探讨实际方案中使用的测量类型及其在方案中的使用频率,以及它们在全球不同国家的敏感性、特异性、假阳性和假阴性方面的结果。

方法

根据系统评价和荟萃分析的首选报告项目进行了系统文献综述。使用 PubMed、Google Scholar 和 Science Direct 等电子数据库进行文献搜索。共确定了 422 篇文章,其中只有 15 篇属于当前研究。对符合研究标准的 15 篇文章进行了综述。综述相关数据和结果,并在以下标题下进行表格化和定性分析:国家;客观筛查和/或诊断措施;筛查方案的详细信息;结果(包括假阳性和假阴性结果、敏感性和/或特异性)、结论和/或建议。然后对这些表格化的发现进行讨论,并提出结论和建议。

结果

本文报告的研究结果基于对审查数据的定性而不是定量分析。一般来说,本综述的研究结果首先表明,新生儿听力筛查中采用的方案缺乏一致性。其次,许多审查的筛查方案包括两个或更多的层次或阶段,瞬态诱发耳声发射(TEOAE)和自动听性脑干反应(AABR)最常用。第三,与 TEOAE 相比,DPOAE 的使用似乎较少。最后,关于常规将 AABR 纳入 NHS 协议的问题仍未得到明确回答。

结论

有充分的证据表明,在 NHS 计划中纳入 AABR 可有效提高听力筛查结果。在测试组合或交叉检查原则中使用 AABR 与 OAE 相结合进行筛查是合适的,但需要系统地研究将 AABR 纳入以促进进行适当的诊断评估。

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