Lam Yuet-Wai, Ao Ningjian
Department of Biomedical Engineering, Jinan University, Guangzhou 510632, P.R.China;Key Laboratory of Biomaterials, Guangdong Provincial Department of Education, Guangzhou 510632, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Oct 25;35(5):805-810. doi: 10.7507/1001-5515.201711045.
Three-dimensional (3D) printing is a low-cost, high-efficiency production method, which can reduce the current cost and increase the profitability of skin repair material industry nowadays, and develop products with better performance. The 3D printing technology commonly used in the preparation of skin repair materials includes fused deposition molding technology and 3D bioprinting technology. Fused deposition molding technology has the advantages of simple and light equipment, but insufficient material selection. 3D bioprinting technology has more materials to choose from, but the equipment is cumbersome and expensive. In recent years, research on both technologies has focused on the development and application of materials. This article details the principles of fused deposition modeling and 3D bioprinting, research advances in wound dressings and tissue engineering skin production, and future developments in 3D printing on skin tissue repair, including cosmetic restoration and biomimetic tissue engineering. Also, this review prospects the development of 3D printing technology in skin tissue repairment.
三维(3D)打印是一种低成本、高效率的生产方法,它可以降低当前成本,提高如今皮肤修复材料行业的盈利能力,并开发出性能更好的产品。用于制备皮肤修复材料的3D打印技术包括熔融沉积成型技术和3D生物打印技术。熔融沉积成型技术具有设备简单轻便的优点,但材料选择不足。3D生物打印技术有更多的材料可供选择,但设备笨重且昂贵。近年来,对这两种技术的研究都集中在材料的开发和应用上。本文详细介绍了熔融沉积建模和3D生物打印的原理、伤口敷料和组织工程皮肤生产的研究进展,以及3D打印在皮肤组织修复方面的未来发展,包括美容修复和仿生组织工程。此外,本综述还展望了3D打印技术在皮肤组织修复中的发展。