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用于伤口敷料应用的聚合物水凝胶膜综述:基于聚乙烯醇的水凝胶敷料

A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings.

作者信息

Kamoun Elbadawy A, Kenawy El-Refaie S, Chen Xin

机构信息

Polymeric Materials Research Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg Al-Arab City 21934, Alexandria, Egypt.

Polymer Research Group, Department of Chemistry, Faculty of Science, University of Tanta, Tanta 31527, Egypt.

出版信息

J Adv Res. 2017 May;8(3):217-233. doi: 10.1016/j.jare.2017.01.005. Epub 2017 Feb 3.

Abstract

This review presents the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications. Many endeavors have been exerted during past ten years for developing new artificial polymeric membranes, which fulfill the demanded conditions for the treatment of skin wounds. This review mainly focuses on representing specifications of ideal polymeric wound dressing membranes, such as crosslinked hydrogels compatible with wound dressing purposes. But as the hydrogels with single component have low mechanical strength, recent trends have offered composite or hybrid hydrogel membranes to achieve the typical wound dressing requirements.

摘要

本综述介绍了过去和当前的研究工作,并简要描述了由生物聚合物和合成聚合物制成的用于伤口敷料应用的水凝胶膜的特性。在过去十年中,人们为开发新型人工聚合物膜付出了诸多努力,这些膜满足了治疗皮肤伤口的要求。本综述主要关注理想的聚合物伤口敷料膜的特性,例如与伤口敷料目的相兼容的交联水凝胶。但由于单组分水凝胶的机械强度较低,最近的趋势是提供复合或混合水凝胶膜以满足典型的伤口敷料要求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ec9/5315442/fbe177fe3b75/fx2.jpg

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