Mishra Abhay, Srivastava Vivek
Department of Mechanical Engineering, DIT University, Dehradun, India.
J Med Eng Technol. 2021 May;45(4):290-302. doi: 10.1080/03091902.2021.1893845. Epub 2021 Apr 30.
An implants' effectiveness depends upon the form of biomaterial used in its manufacture. A suitable material for implants should be biocompatible, sterile, mechanically stable and simple to shape. 3D printing technologies have been breaking new ground in the medical and medical industries in order to build patient-specific devices embedded in bioactive drugs, cells and proteins. Widespread use in medical 3D printing is a broad range of biomaterials including metals, ceramics, polymers and composites. Continuous work and developments in biomaterials used in 3D printing have contributed to significant growth of 3D printing applications in the production of personalised joints, prostheses, medication delivery system and 3D tissue engineering and regenerative medicine scaffolds. The present analysis focuses on the biomaterials used for therapeutic applications in different 3D printing technologies. Many specific forms of medical 3D printing technology are explored in depth, including fused deposition modelling, extrusion-based bioprinting, inkjet and poly-jet printing processes, their therapeutic uses, various types of biomaterial used today and the major shortcoming , are being studied in depth.
植入物的有效性取决于其制造过程中所使用的生物材料的形式。适用于植入物的材料应具有生物相容性、无菌、机械稳定性且易于塑形。3D打印技术在医疗及医疗行业不断开拓新领域，以制造嵌入生物活性药物、细胞和蛋白质的定制化设备。在医疗3D打印中广泛使用的是包括金属、陶瓷、聚合物和复合材料在内的多种生物材料。3D打印中使用的生物材料的持续研究与发展推动了3D打印在个性化关节、假体、药物输送系统以及3D组织工程和再生医学支架生产中的应用显著增长。本分析聚焦于不同3D打印技术中用于治疗应用的生物材料。深入探讨了许多特定形式的医疗3D打印技术，包括熔融沉积建模、挤出式生物打印、喷墨和多喷射打印工艺、它们的治疗用途、当今使用的各种生物材料类型以及主要缺点。
