Gök Kevser, Cengiz Gizem, Erol Kemal, Özgöçmen Salih
Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Medical Faculty of Erciyes University, Kayseri, Turkey.
Arch Rheumatol. 2016 May 17;31(4):329-332. doi: 10.5606/ArchRheumatol.2016.5909. eCollection 2016 Dec.
This study aims to evaluate the reproducibility of Turkish versions of multidimensional assessment of fatigue (MAF) and fatigue severity scales (FSS) and the relationship between health related quality of life, disability, and psychological status in patients with systemic sclerosis (SSc).
A total of 21 female patients (mean age 47.14±10.39 years; range 18 to 75 years) who met 2013 American College of Rheumatology/European League Against Rheumatism criteria for SSc were evaluated for severity of organ involvement and symptoms. Turkish version of MAF, FSS, and visual analog scale of fatigue were assessed at baseline and after two to three weeks. Level of dyspnea was noted and disability, functional limitation, and quality of life were assessed by health assessment questionnaire, 6-minute walking distance, and short-form 36, respectively.
Ten patients had diffuse and 11 had limited SSc. MAF subscales and FSS had significant correlations with short-form 36-vitality subscale and 6-minute walking distance. Intraclass correlation coefficients for FSS and visual analog scale of fatigue were 0.824 (95% confidence interval, 0.566- 0.929) and 0.932 (95% confidence interval, 0.832-0.972), respectively. The intraclass correlation coefficients for MAF subscales changed between 0.916 and 0.968, except for MAF-timing (intraclass correlation coefficient, 0.404).
Our results revealed that FSS and MAF subscales had high reproducibility and correlated well with quality of life and disability scales which, to some extent, may suggest convergent validity of MAF subscales and FSS in SSc. The incompatible nature and four-choice answering in two items of MAF-timing may be the underlying reason for trivial relationship with other parameters. The Turkish version of MAF and FSS may be used to assess fatigue in patients with SSc.
本研究旨在评估土耳其语版多维疲劳评估量表（MAF）和疲劳严重程度量表（FSS）的可重复性，以及系统性硬化症（SSc）患者健康相关生活质量、残疾与心理状态之间的关系。
总共21名符合2013年美国风湿病学会/欧洲抗风湿病联盟SSc标准的女性患者（平均年龄47.14±10.39岁；年龄范围18至75岁）接受了器官受累严重程度和症状评估。在基线以及两到三周后评估土耳其语版MAF、FSS和疲劳视觉模拟量表。记录呼吸困难程度，并分别通过健康评估问卷、6分钟步行距离和简短健康调查问卷36项来评估残疾、功能受限和生活质量。
10名患者患有弥漫性SSc，11名患者患有局限性SSc。MAF各子量表和FSS与简短健康调查问卷36项活力子量表及6分钟步行距离显著相关。FSS和疲劳视觉模拟量表的组内相关系数分别为0.824（95%置信区间，0.566 - 0.929）和0.932（95%置信区间，0.832 - 0.972）。MAF各子量表的组内相关系数在0.916至0.968之间变化，但MAF - 时间维度除外（组内相关系数为0.404）。
我们的结果显示，FSS和MAF各子量表具有高可重复性，且与生活质量及残疾量表相关性良好，这在一定程度上可能提示MAF各子量表和FSS在SSc中的收敛效度。MAF - 时间维度两项内容性质不兼容且为四选一回答方式，可能是其与其他参数关系不显著的潜在原因。土耳其语版MAF和FSS可用于评估SSc患者的疲劳情况。
