Denenberg Sagi, Dubé Maya Bräm
North Toronto Veterinary Behaviour Specialty Clinic, Toronto, Canada; Langford Vets, University of Bristol, UK.
Division of Animal Welfare, Veterinary Public Health Institute, Vetsuisse Faculty, University of Berne, Switzerland.
J Feline Med Surg. 2018 Nov;20(11):1034-1045. doi: 10.1177/1098612X18806760.
When a cat is presented for evaluation of a problem behaviour, it is likely that the cat's wellbeing is negatively affected by the condition. In addition, the owners and any other animals around the cat may also be experiencing negative consequences. When managing these cases, it is important to consider all options (including behaviour modification, environmental changes, medications) that can help to reach an optimal solution. Medication cannot teach the cat how to behave or change a particular behaviour; it can, however, reduce arousal, excitability, reactivity and anxiety.
The rationale for using psychoactive medications in behavioural medicine, or veterinary psychiatry, is to increase the wellbeing of the animal and to aid the owner and practitioner in managing problem behaviours. Medications should always be used as an adjunct to behavioural and environmental modification.
Many psychoactive medications cannot be used in the face of certain physical illnesses or concurrently with other medications. Some medications may also have side effects, not be effective at the recommended dose or have a paradoxical effect. Furthermore, success is reliant on the owner being able to administer the medication.
This article aims to guide practitioners by discussing questions such as how to choose the appropriate medication, how to dose it and how long to use it. The psychoactive medications most commonly used in feline medicine are reviewed, as well as some that are newer or less common.
Data for the use of medications in cats is limited, with just a small number of clinical-, species- and problem-directed studies available, and a few more case series and case reports. Where feline-specific research is not available, the authors have drawn upon research published in other species, such as humans, dogs and rats, as well as anecdotal reports and expert opinions.
当一只猫因问题行为接受评估时,其健康状况很可能已受到该状况的负面影响。此外,猫的主人以及周围的其他动物也可能正在经历负面后果。在处理这些病例时,重要的是要考虑所有有助于达成最佳解决方案的选项(包括行为矫正、环境改变、药物治疗)。药物不能教会猫如何表现或改变特定行为;然而,它可以降低唤醒水平、兴奋性、反应性和焦虑感。
在行为医学或兽医精神病学中使用精神活性药物的理论依据是提高动物的健康水平,并帮助主人和从业者管理问题行为。药物应始终作为行为和环境改变的辅助手段使用。
面对某些身体疾病或与其他药物同时使用时,许多精神活性药物无法使用。一些药物也可能有副作用,在推荐剂量下无效或产生矛盾效应。此外,成功与否取决于主人能否给药。
本文旨在通过讨论如何选择合适的药物、如何给药以及使用多长时间等问题来指导从业者。文中回顾了猫科医学中最常用的精神活性药物,以及一些较新的或不太常见的药物。
猫使用药物的数据有限,仅有少量针对临床、物种和问题的研究,以及一些病例系列和病例报告。在没有猫特异性研究的情况下,作者借鉴了在其他物种(如人类、狗和大鼠)中发表的研究,以及轶事报告和专家意见。