Jin Harry, Restar Arjee, Biello Katie, Kuhns Lisa, Reisner Sari, Garofalo Robert, Mimiaga Matthew J
a Department of Epidemiology , Brown University School of Public Health , Providence , USA.
b Department of Behavioral and Social Sciences , Brown University School of Public Health , Providence , USA.
AIDS Care. 2019 Jan;31(1):125-130. doi: 10.1080/09540121.2018.1539213. Epub 2018 Oct 31.
Young transgender women (YTW) are disproportionately affected by HIV, however, little is known about the factors associated with HIV infection and treatment engagement. We examined correlates of HIV infection and the steps of the HIV treatment cascade, specifically, being aware of their HIV infection, linked to care, on ART, and adherent to ART. We analyzed the baseline data of Project LifeSkills, a randomized control trial of sexually active YTW recruited from Chicago, Illinois and Boston, Massachusetts. We conducted multivariable Poisson regressions to evaluate correlates of HIV infection and the steps of the HIV treatment cascade. Nearly a quarter (24.7%) of YTW were HIV-infected. Among HIV-infected YTW, 86.2% were aware of their HIV status, 72.3% were linked to care, 56.9% were on ART, and 46.2% were adherent to ART. Having avoided healthcare due to cost in the past 12 months and not having a primary care provider were associated with suboptimal engagement in HIV care. Our results suggest that improving linkage and retention in care by addressing financial barriers and improving access to primary care providers could significantly improve health outcomes of YTW as well as reduce forward transmission of HIV.
年轻的跨性别女性(YTW)受艾滋病毒影响的比例过高,然而,对于与艾滋病毒感染及治疗参与相关的因素却知之甚少。我们研究了艾滋病毒感染的相关因素以及艾滋病毒治疗流程的各个环节,具体包括知晓自身感染艾滋病毒、与医疗服务建立联系、接受抗逆转录病毒治疗(ART)以及坚持接受ART治疗。我们分析了“生活技能项目”的基线数据,该项目是一项针对从伊利诺伊州芝加哥市和马萨诸塞州波士顿市招募的性活跃YTW的随机对照试验。我们进行了多变量泊松回归分析,以评估艾滋病毒感染的相关因素以及艾滋病毒治疗流程的各个环节。近四分之一(24.7%)的YTW感染了艾滋病毒。在感染艾滋病毒的YTW中,86.2%知晓自己的艾滋病毒感染状况,72.3%与医疗服务建立了联系,56.9%接受了ART治疗,46.2%坚持接受ART治疗。在过去12个月因费用问题而未寻求医疗服务以及没有初级保健提供者与艾滋病毒治疗的参与度欠佳有关。我们的研究结果表明,通过消除经济障碍并改善获得初级保健提供者服务的机会来加强与医疗服务的联系并提高留存率,可显著改善YTW的健康状况,并减少艾滋病毒的进一步传播。