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青少年睡眠时间与高血压之间的关联:一项系统评价和荟萃分析。

Association between sleep duration and high blood pressure in adolescents: a systematic review and meta-analysis.

作者信息

Jiang Wen, Hu Chengyang, Li Fengli, Hua Xiaoguo, Zhang Xiujun

机构信息

a Department of Epidemiology and Biostatistics, School of Public Health , Anhui Medical University , Hefei , China.

出版信息

Ann Hum Biol. 2018 Sep-Dec;45(6-8):457-462. doi: 10.1080/03014460.2018.1535661. Epub 2019 Jan 21.

DOI:10.1080/03014460.2018.1535661
PMID:30387692
Abstract

CONTEXT

Sleep has been assessed as a risk factor for health consequences. Among adults, excessively longer and shorter sleep durations are associated with high blood pressure (BP), but knowledge of the association between sleep duration and high BP among adolescents is limited.

OBJECTIVES

To estimate the associations between sleep duration and high BP in adolescents.

METHODS

PubMed, Web of Science, and Cochrane databases were searched for eligible publications up until 20 November 2017. This study reviewed the reference lists from retrieved articles to search for relevant studies. Pooled odds ratios (ORs) were calculated using a random-effects meta-analysis. Sub-group and sensitivity analyses were conducted to identify heterogeneity. Publication bias was evaluated using Egger's test.

RESULTS

Seven studies involving 21,150 participants were included, with ages ranging from 10-18 years. For primary analysis, compared with the reference sleep duration, the pooled OR for high BP was 1.51 (95% confidence interval [CI] = 1.04-2.19) for the short sleep duration overall. For long sleep duration, the pooled OR was 1.04 (95% CI = 0.78-1.38). Further sub-group analysis showed that short sleep duration had a higher risk of incident high BP in males (OR = 1.55, 95% CI = 1.24-1.93) than in females (OR = 1.23, 95% CI = 0.47-3.22).

CONCLUSIONS

Among adolescents, and particularly male adolescents, short sleep duration may be a risk factor for high BP. More attention should be given to this lifestyle factor.

摘要

背景

睡眠已被评估为健康后果的一个风险因素。在成年人中,睡眠时间过长和过短都与高血压(BP)有关,但关于青少年睡眠时间与高血压之间关联的知识有限。

目的

评估青少年睡眠时间与高血压之间的关联。

方法

检索了PubMed、科学网和Cochrane数据库,以查找截至2017年11月20日的符合条件的出版物。本研究回顾了检索到的文章的参考文献列表,以查找相关研究。使用随机效应荟萃分析计算合并比值比(OR)。进行亚组和敏感性分析以识别异质性。使用Egger检验评估发表偏倚。

结果

纳入了7项研究,共21150名参与者,年龄在10至18岁之间。对于主要分析,与参考睡眠时间相比,总体上短睡眠时间的高血压合并OR为1.51(95%置信区间[CI]=1.04-2.19)。对于长睡眠时间,合并OR为1.04(95%CI=0.78-1.38)。进一步的亚组分析表明,男性(OR=1.55,95%CI=1.24-1.93)的短睡眠时间发生高血压的风险高于女性(OR=1.23,95%CI=0.47-3.22)。

结论

在青少年中,尤其是男性青少年,短睡眠时间可能是高血压的一个风险因素。应更多关注这一生活方式因素。

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