对多样性造成压力。
Putting a strain on diversity.
机构信息
Glasgow Ageing Research Network (GARNER), Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, UK.
Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA.
出版信息
EMBO J. 2018 Nov 15;37(22). doi: 10.15252/embj.2018100862. Epub 2018 Nov 2.
Abstract
Human life expectancy is increasing on a global scale, but healthspan—the period of life free from age‐associated ill health—is not improving at a comparable rate. This disconnect means that a greater proportion of the general population will spend a longer period of their life suffering from one or more debilitating age‐associated diseases, such as cardiovascular disease, Alzheimer's disease, osteoporosis, sarcopenia and various cancers. Understanding the processes underlying ageing and age‐related diseases is therefore a major and pressing research challenge in biomedical research.
摘要
全球范围内，人类的预期寿命在不断延长，但健康预期寿命（即没有与年龄相关的健康问题的寿命）并没有以同样的速度提高。这种脱节意味着越来越多的普通民众将在他们的生命中更长的时间里遭受一种或多种使人衰弱的与年龄相关的疾病，如心血管疾病、阿尔茨海默病、骨质疏松症、肌肉减少症和各种癌症。因此，了解衰老和与年龄相关的疾病的背后过程是生物医学研究中的一个重大而紧迫的研究挑战。
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