Division of Allergy & Immunology, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Division of Allergy & Immunology, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
J Allergy Clin Immunol Pract. 2018 Nov-Dec;6(6):1835-1842. doi: 10.1016/j.jaip.2018.08.014.
Since the initial discovery of aeroallergens in the 20th century, our understanding of their properties including sources and factors influencing their spread continues to expand. Both habits of daily living and the presence of environmental factors such as exposure to animals or pollution can influence susceptibility to atopic disease. Because relevant allergens may vary in individuals and communities, it is necessary to understand the physical properties of environmental aeroallergens that are associated with clinical disease to explain symptoms and to implement successful integrated interventions. The objective of this review was to present an overview of aeroallergens and the environmental factors influencing their current distribution. Using historical studies along with recent advancements, we will give an up-to-date description of the physical characteristics and aerodynamics of aeroallergens in addition to location, quantities, and timing of exposure.
自 20 世纪首次发现空气过敏原以来，我们对其特性（包括来源和影响其传播的因素）的了解不断扩展。日常生活习惯以及环境因素（如接触动物或污染）的存在都会影响特应性疾病的易感性。由于相关过敏原在个体和社区中可能有所不同，因此有必要了解与临床疾病相关的环境空气过敏原的物理特性，以解释症状并实施成功的综合干预措施。本综述的目的是概述空气过敏原以及影响其当前分布的环境因素。我们将使用历史研究以及最新进展，除了暴露的位置、数量和时间外，还对空气过敏原的物理特性和空气动力学特性进行最新描述。
