Anjum Sumaira, Ishaque Sara, Fatima Hijab, Farooq Wajiha, Hano Christophe, Abbasi Bilal Haider, Anjum Iram
Department of Biotechnology, Kinnaird College for Women, Lahore 54000, Pakistan.
Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), INRAe USC1328, Université d'Orléans, 28000 Chartres, France.
Pharmaceuticals (Basel). 2021 Jul 21;14(8):707. doi: 10.3390/ph14080707.
Healthcare, as a basic human right, has often become the focus of the development of innovative technologies. Technological progress has significantly contributed to the provision of high-quality, on-time, acceptable, and affordable healthcare. Advancements in nanoscience have led to the emergence of a new generation of nanostructures. Each of them has a unique set of properties that account for their astonishing applications. Since its inception, nanotechnology has continuously affected healthcare and has exerted a tremendous influence on its transformation, contributing to better outcomes. In the last two decades, the world has seen nanotechnology taking steps towards its omnipresence and the process has been accelerated by extensive research in various healthcare sectors. The inclusion of nanotechnology and its allied nanocarriers/nanosystems in medicine is known as nanomedicine, a field that has brought about numerous benefits in disease prevention, diagnosis, and treatment. Various nanosystems have been found to be better candidates for theranostic purposes, in contrast to conventional ones. This review paper will shed light on medically significant nanosystems, as well as their applications and limitations in areas such as gene therapy, targeted drug delivery, and in the treatment of cancer and various genetic diseases. Although nanotechnology holds immense potential, it is yet to be exploited. More efforts need to be directed to overcome these limitations and make full use of its potential in order to revolutionize the healthcare sector in near future.
医疗保健作为一项基本人权,常常成为创新技术发展的焦点。技术进步为提供高质量、及时、可接受且负担得起的医疗保健做出了重大贡献。纳米科学的进步催生了新一代纳米结构。它们每一个都具有独特的性质组合,这解释了它们令人惊叹的应用。自诞生以来,纳米技术不断影响着医疗保健,并对其变革产生了巨大影响,带来了更好的结果。在过去二十年里,世界见证了纳米技术走向无所不在,并且各个医疗保健领域的广泛研究加速了这一进程。将纳米技术及其相关纳米载体/纳米系统应用于医学被称为纳米医学,这一领域在疾病预防、诊断和治疗方面带来了诸多益处。与传统系统相比,各种纳米系统已被发现更适合用于诊疗目的。这篇综述文章将阐明具有医学意义的纳米系统,以及它们在基因治疗、靶向药物递送、癌症和各种遗传疾病治疗等领域的应用和局限性。尽管纳米技术拥有巨大潜力,但尚未得到充分利用。需要付出更多努力来克服这些局限性,并充分发挥其潜力,以便在不久的将来彻底改变医疗保健行业。