Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, 2000, Jintong Road, Tangjiawan, Zhuhai 519087, China.
Molecules. 2018 Nov 5;23(11):2880. doi: 10.3390/molecules23112880.
Obesity is a group of metabolic disorders caused by multiple factors, including heredity, diet, lifestyle, societal determinants, environment, and infectious agents, which can all lead to the enhancement of storage body fat. Excess visceral fat mass in adipose tissue generate several metabolic disorders, including cardiovascular diseases with chronic inflammation based pathophysiology. The objective of the current review is to summarize the cellular mechanisms of obesity that attenuate by antioxidant potentials of medicinal and edible mushrooms. Studies have showed that mushrooms potentially have antioxidant capacities, which increase the antioxidant defense systems in cells. They boost anti-inflammatory actions and thereby protect against obesity-related hypertension and dyslipidemia. The practice of regular consumption of mushrooms is effective in the treatment of metabolic syndrome, including obesity, and thus could be a good candidate for use in future pharmaceutical or nutraceutical applications.
肥胖是一组由多种因素引起的代谢紊乱，包括遗传、饮食、生活方式、社会决定因素、环境和感染因子，这些因素都可能导致储存体脂肪增加。脂肪组织中过多的内脏脂肪会导致多种代谢紊乱，包括基于慢性炎症病理生理学的心血管疾病。本综述的目的是总结肥胖的细胞机制，这些机制可被药用和食用蘑菇的抗氧化潜力所减弱。研究表明，蘑菇具有潜在的抗氧化能力，可以增加细胞中的抗氧化防御系统。它们增强抗炎作用，从而预防与肥胖相关的高血压和血脂异常。定期食用蘑菇的做法对治疗代谢综合征，包括肥胖症是有效的，因此可能是未来药物或营养应用的良好候选物。
