Almeras Lionel, Basco Leonardo K, Sokhna Cheikh, Ranque Stéphane, Parola Philippe, Devaux Christian, Brouqui Philippe, Drancourt Michel, Pradines Bruno
Unité Parasitologie et entomologie, Département des maladies infectieuses, Institut de recherche biomédicale des armées, Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France.
Aix-Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.
New Microbes New Infect. 2018 Jul 4;26:S23-S30. doi: 10.1016/j.nmni.2018.06.003. eCollection 2018 Nov.
The Institut Hospitalo-Universitaire Méditerranée Infection is positioned for the diagnosis, prevention and treatment of the 'big three' killer diseases: malaria, tuberculosis and HIV. We implemented the use of new diagnostic samples such as stools and new diagnostic tests such as mass spectrometry for the dual identification of vectors and pathogens. Furthermore, advances in the prevention and treatment of malaria and tuberculosis are reviewed, along with advances in the understanding of the role of microbiota in the resistance to HIV infection. These achievements represent a major step towards a better management of the 'big three' diseases worldwide.
地中海感染大学医院研究所致力于疟疾、结核病和艾滋病这三大致命疾病的诊断、预防和治疗。我们采用了新的诊断样本(如粪便)和新的诊断测试(如质谱分析法)来双重鉴定病媒和病原体。此外,还综述了疟疾和结核病预防与治疗方面的进展,以及对微生物群在抵抗艾滋病毒感染中所起作用的认识进展。这些成果是朝着在全球更好地管理这三大疾病迈出的重要一步。