Eyerich S, Traidl-Hoffmann C, Behrendt H, Cavani A, Schmidt-Weber C B, Ring J, Eyerich K
ZAUM - Zentrum Allergie & Umwelt, Technische Universität und Helmholtz-Zentrum München, Munich, Germany.
Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Munich, Germany.
Allergol Select. 2017 Aug 4;1(1):71-76. doi: 10.5414/ALX01403E. eCollection 2017.
The biology of the T cell cytokines Interleukin (IL-)17 and IL-22 has been a main focus in the field of clinical immunology in the last decade. This intensive interest in both cytokines has resulted in almost 5,000 scientific publications (www.pubmed.com) dealing with the molecular structure, extra- and intracellular signaling pathways, specific transcription factors and the function of IL-17 and IL-22. This review article highlights the main findings concerning IL-17 and IL-22 in the last years.
在过去十年中，T细胞细胞因子白细胞介素（IL-）17和IL-22的生物学一直是临床免疫学领域的主要研究重点。对这两种细胞因子的浓厚兴趣已产生了近5000篇科学出版物（www.pubmed.com），涉及IL-17和IL-22的分子结构、细胞外和细胞内信号通路、特定转录因子以及功能。这篇综述文章重点介绍了近年来有关IL-17和IL-22的主要研究发现。
