兔肝中的甲酰-亚甲基-次甲基四氢叶酸合成酶（复合形式）。5,10-亚甲基四氢叶酸转化为10-甲酰四氢叶酸过程中单一作用位点的证据。 - Suppr

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超能文献

Formyl-methenyl-methylenetetrahydrofolate synthetase from rabbit liver (combined). Evidence for a single site in the conversion of 5,10-methylenetetrahydrofolate to 10-formyltetrahydrofolate.

作者信息

Schirch L

出版信息

Arch Biochem Biophys. 1978 Aug;189(2):283-90. doi: 10.1016/0003-9861(78)90214-x.

DOI:10.1016/0003-9861(78)90214-x

PMID:30404

Abstract

摘要

相似文献

Formyl-methenyl-methylenetetrahydrofolate synthetase from rabbit liver (combined). Evidence for a single site in the conversion of 5,10-methylenetetrahydrofolate to 10-formyltetrahydrofolate.兔肝中的甲酰-亚甲基-次甲基四氢叶酸合成酶（复合形式）。5,10-亚甲基四氢叶酸转化为10-甲酰四氢叶酸过程中单一作用位点的证据。

Arch Biochem Biophys. 1978 Aug;189(2):283-90. doi: 10.1016/0003-9861(78)90214-x.

The effect of nitrous oxide-induced inactivation of vitamin B12 on the activity of formyl-methenyl-methylenetetrahydrofolate synthetase, methylene-tetrahydrofolate reductase and formiminotetrahydrofolate transferase.一氧化二氮诱导的维生素B12失活对甲酰-亚甲基-亚甲基四氢叶酸合成酶、亚甲基四氢叶酸还原酶和亚胺甲基四氢叶酸转移酶活性的影响。

Biochem Biophys Res Commun. 1980 Dec 31;97(4):1329-33. doi: 10.1016/s0006-291x(80)80012-x.

Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase from porcine liver. Interaction between the dehydrogenase and cyclohydrolase activities of the multifunctional enzyme.猪肝中的亚甲基四氢叶酸脱氢酶-亚甲基四氢叶酸环化水解酶-甲酰四氢叶酸合成酶。多功能酶的脱氢酶和环化水解酶活性之间的相互作用。

Biochim Biophys Acta. 1978 Feb 10;522(2):311-7. doi: 10.1016/0005-2744(78)90065-7.

Kinetic relationships between the various activities of the formyl-methenyl-methylenetetrahydrofolate synthetase.甲酰-亚甲基-亚甲基四氢叶酸合成酶各种活性之间的动力学关系。

Biochemistry. 1983 Mar 1;22(5):1005-13. doi: 10.1021/bi00274a002.

Formyl-methenyl-methylenetetrahydrofolate synthetase (combined): a multifunctional protein in eukaryotic folate metabolism.甲酰-亚甲基-次甲基四氢叶酸合成酶（复合）：真核生物叶酸代谢中的一种多功能蛋白。

Methods Enzymol. 1980;66:616-26. doi: 10.1016/0076-6879(80)66515-x.

Mutants of formyltetrahydrofolate interconversion pathway of Saccharomyces cerevisiae.酿酒酵母甲酰四氢叶酸相互转化途径的突变体

Genetics. 1977 May;86(1):85-102. doi: 10.1093/genetics/86.1.85.

C1-Tetrahydrofolate synthase from rabbit liver. Structural and kinetic properties of the enzyme and its two domains.来自兔肝的C1-四氢叶酸合酶。该酶及其两个结构域的结构和动力学特性。

J Biol Chem. 1985 Feb 25;260(4):2245-52.

Formyl-methenyl-methylenetetrahydrofolate synthetase(combined) from yeast. Biochemical characterization of the protein from an ade3 mutant lacking the formyltetrahydrofolate synthetase function.来自酵母的甲酰-亚甲基-亚甲基四氢叶酸合成酶（组合型）。缺乏甲酰四氢叶酸合成酶功能的ade3突变体中该蛋白质的生化特性。

J Biol Chem. 1980 Mar 25;255(6):2569-77.

Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate-cyclohydrolase-formyltetrahy dro folate synthetase. Affinity labelling of the dehydrogenase-cyclohydrolase active site.亚甲基四氢叶酸脱氢酶-亚甲基四氢叶酸环化水解酶-甲酰四氢叶酸合成酶。脱氢酶-环化水解酶活性位点的亲和标记。

Biochem Biophys Res Commun. 1985 Apr 16;128(1):148-54. doi: 10.1016/0006-291x(85)91657-2.

10-Formyltetrahydrofolate synthetase. Evidence for a conformational change in the enzyme upon binding of tetrahydropteroylpolyglutamates.10-甲酰四氢叶酸合成酶。四氢蝶酰多聚谷氨酸结合后酶构象变化的证据。

J Biol Chem. 1987 Sep 15;262(26):12519-25.

引用本文的文献

Mammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues.哺乳动物 MTHFD2L 编码一种在线粒体中表达的亚甲基四氢叶酸脱氢酶同工酶，存在于成年组织中。

J Biol Chem. 2011 Feb 18;286(7):5166-74. doi: 10.1074/jbc.M110.196840. Epub 2010 Dec 16.

Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.线粒体 C1-四氢叶酸合成酶（MTHFD1L）支持线粒体一碳单位在胚胎中流入甲基循环。

J Biol Chem. 2010 Feb 12;285(7):4612-20. doi: 10.1074/jbc.M109.079855. Epub 2009 Nov 30.

A mathematical model gives insights into the effects of vitamin B-6 deficiency on 1-carbon and glutathione metabolism.一个数学模型深入揭示了维生素B-6缺乏对一碳代谢和谷胱甘肽代谢的影响。

J Nutr. 2009 Apr;139(4):784-91. doi: 10.3945/jn.109.104265. Epub 2009 Feb 25.

The crystal structure of a bacterial, bifunctional 5,10 methylene-tetrahydrofolate dehydrogenase/cyclohydrolase.一种细菌双功能5,10-亚甲基四氢叶酸脱氢酶/环水解酶的晶体结构。

Protein Sci. 1999 Jun;8(6):1342-9. doi: 10.1110/ps.8.6.1342.

Immunological crossreactivity of eukaryotic C1-tetrahydrofolate synthase and prokaryotic 10-formyltetrahydrofolate synthetase.真核生物C1-四氢叶酸合酶与原核生物10-甲酰四氢叶酸合成酶的免疫交叉反应性。

Proc Natl Acad Sci U S A. 1983 Nov;80(22):6799-803. doi: 10.1073/pnas.80.22.6799.

Serine hydroxymethyltransferase from Escherichia coli: purification and properties.来自大肠杆菌的丝氨酸羟甲基转移酶：纯化及性质

J Bacteriol. 1985 Jul;163(1):1-7. doi: 10.1128/jb.163.1.1-7.1985.

Distribution of 10-formyltetrahydrofolate synthetase in eubacteria.10-甲酰四氢叶酸合成酶在真细菌中的分布

J Bacteriol. 1988 Feb;170(2):995-7. doi: 10.1128/jb.170.2.995-997.1988.

Cloning and expression in Escherichia coli of the gene for 10-formyltetrahydrofolate synthetase from Clostridium acidiurici ("Clostridium acidi-urici").来自尿酸梭菌（“Clostridium acidi-urici”）的10-甲酰四氢叶酸合成酶基因在大肠杆菌中的克隆与表达。

J Bacteriol. 1986 Jul;167(1):205-9. doi: 10.1128/jb.167.1.205-209.1986.

Nucleotide sequence of the Clostridium acidiurici ("Clostridium acidi-urici") gene for 10-formyltetrahydrofolate synthetase shows extensive amino acid homology with the trifunctional enzyme C1-tetrahydrofolate synthase from Saccharomyces cerevisiae.尿酸梭菌（“Clostridium acidi-urici”）中10-甲酰四氢叶酸合成酶基因的核苷酸序列与酿酒酵母的三功能酶C1-四氢叶酸合成酶显示出广泛的氨基酸同源性。

J Bacteriol. 1988 Jul;170(7):3255-61. doi: 10.1128/jb.170.7.3255-3261.1988.

Mutations in ADE3 reduce the efficiency of the omnipotent suppressor sup45-2.ADE3中的突变会降低全能抑制因子sup45-2的效率。

Curr Genet. 1989 Dec;16(5-6):315-21. doi: 10.1007/BF00340709.

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