10-甲酰四氢叶酸合成酶在真细菌中的分布
Distribution of 10-formyltetrahydrofolate synthetase in eubacteria.
作者信息
Whitehead T R, Park M, Rabinowitz J C
机构信息
Department of Biochemistry, University of California, Berkeley 94720.
出版信息
J Bacteriol. 1988 Feb;170(2):995-7. doi: 10.1128/jb.170.2.995-997.1988.
Abstract
The distribution of 10-formyltetrahydrofolate synthetase, which activates formate for use as a one-carbon donor in a variety of biosynthetic reactions, was determined for a variety of eubacteria. Organisms from several genera were found to lack detectable synthetase activity; however, all organisms tested were found to contain 5,10-methylenetetrahydrofolate dehydrogenase activity.
摘要
测定了多种真细菌中10-甲酰四氢叶酸合成酶的分布情况，该酶可激活甲酸，使其在多种生物合成反应中用作一碳供体。发现几个属的生物缺乏可检测到的合成酶活性；然而，所有测试的生物均含有5,10-亚甲基四氢叶酸脱氢酶活性。
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