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人类杀伤性淋巴细胞的表面特征

Surface characteristics of the human K (killer) lymphocyte.

作者信息

Eremin O, Kraft D, Coombs R R, Franks D, Ashby J, Plumb D

出版信息

Int Arch Allergy Appl Immunol. 1977;55(1-6):112-25. doi: 10.1159/000231917.

Abstract

The human non-allergized K (killer) lymphocyte has been characterized using selective depletion and isolation procedures based on surface markers. It was found to be a non-thymus-dependent, Fc-receptor-bearing cell. In an area which is controversial, our findings also indicate that the cell has immunoglobulin on its surface but lacks the receptor for the C3 component of complement (mouse). This would suggest it to be an (Fc + C3-) B lymphocyte.

摘要

人类未致敏的K(杀伤)淋巴细胞已通过基于表面标志物的选择性去除和分离程序进行了表征。发现它是一种非胸腺依赖性、带有Fc受体的细胞。在一个存在争议的领域,我们的研究结果还表明,该细胞表面有免疫球蛋白,但缺乏补体C3成分(小鼠)的受体。这表明它是一种(Fc + C3-)B淋巴细胞。

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