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国家公共部门项目中的暴露前预防推广:肯尼亚案例研究

Pre-exposure prophylaxis rollout in a national public sector program: the Kenyan case study.

作者信息

Masyuko Sarah, Mukui Irene, Njathi Olivia, Kimani Maureen, Oluoch Patricia, Wamicwe Joyce, Mutegi Jane, Njogo Susan, Anyona Micah, Muchiri Phillip, Maikweki Lucy, Musyoki Helgar, Bahati Prince, Kyongo Jordan, Marwa Tom, Irungu Elizabeth, Kiragu Michael, Kioko Urbanus, Ogando Justus, Were Dan, Bartilol Kigen, Sirengo Martin, Mugo Nelly, Baeten Jared M, Cherutich Peter, PrEP Technical Working Group On Behalf Of The

机构信息

The National AIDS and STI Control Program, Ministry of Health, Afya Annex, Kenyatta National Hospital Grounds, Nairobi, Kenya.

Clinton Health Access Initiative, Timau Plaza, 3rd Floor, Argwings Kodhek Road, Nairobi, Kenya.

出版信息

Sex Health. 2018 Nov;15(6):578-586. doi: 10.1071/SH18090.

Abstract

UNLABELLED

Background While advances have been made in HIV prevention and treatment, new HIV infections continue to occur. The introduction of pre-exposure prophylaxis (PrEP) as an additional HIV prevention option for those at high risk of HIV may change the landscape of the HIV epidemic, especially in sub-Saharan Africa, which bears the greatest HIV burden.

METHODS

This paper details Kenya's experience of PrEP rollout as a national public sector program. The process of a national rollout of PrEP guidance, partnerships, challenges, lessons learnt and progress related to national scale up of PrEP in Kenya, as of 2018, is described. National rollout of PrEP was strongly lead by the government, and work was executed through a multidisciplinary, multi-organisation dedicated team. This required reviewing available evidence, providing guidance to health providers, integration into existing logistic and health information systems, robust communication and community engagement. Mapping of the response showed that subnational levels had existing infrastructure but required targeted resources to catalyse PrEP provision. Rollout scenarios were developed and adopted, with prioritisation of 19 counties focusing on high incidence area and high potential PrEP users to maximise impact and minimise costs.

RESULTS

PrEP is now offered in over 900 facilities countrywide. There are currently over 14000 PrEP users 1 year after launching PrEP.

CONCLUSIONS

Kenya becomes the first African country to rollout PrEP as a national program, in the public sector. This case study will provide guidance for low- and middle-income countries planning the rollout of PrEP in response to both generalised and concentrated epidemics.

摘要

未标注

背景 尽管在艾滋病毒预防和治疗方面取得了进展,但新的艾滋病毒感染仍在继续发生。暴露前预防(PrEP)作为一种针对艾滋病毒高风险人群的额外艾滋病毒预防选择,其引入可能会改变艾滋病毒流行的格局,特别是在承受着最大艾滋病毒负担的撒哈拉以南非洲地区。

方法

本文详细介绍了肯尼亚作为国家公共部门项目推出PrEP的经验。描述了截至2018年肯尼亚在全国范围内推出PrEP指南、伙伴关系、挑战、经验教训以及与扩大PrEP规模相关的进展情况。PrEP的全国推广由政府大力牵头,工作通过一个多学科、多组织的专门团队来执行。这需要审查现有证据、为医疗服务提供者提供指导、融入现有的后勤和健康信息系统、进行有力的宣传以及社区参与。对应对措施的梳理表明,地方各级已有基础设施,但需要有针对性的资源来推动PrEP的提供。制定并采用了推广方案,优先考虑19个县,重点是高发病率地区和高潜在PrEP使用者,以最大限度地扩大影响并降低成本。

结果

目前全国有900多个机构提供PrEP。PrEP推出1年后,目前有超过14000名PrEP使用者。

结论

肯尼亚成为非洲首个在公共部门将PrEP作为国家项目推出的国家。本案例研究将为计划推出PrEP以应对广泛流行和集中流行的中低收入国家提供指导。

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