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来自艾伯塔省农业和林业疾病调查项目(2006 - 2014年)的牛亚种分离株的抗菌药物耐药性。

Antimicrobial resistance of bovine ssp. isolates from the Alberta Agriculture and Forestry Disease Investigation Program (2006-2014).

作者信息

Otto Simon J G, Ponich Katrina L, Cassis Rashed, Goertz Carol, Peters Delores, Checkley Sylvia L

机构信息

Animal Health Section, Animal Health and Assurance Branch (Otto, Peters), Agri-Food Laboratories Section, Food Safety Branch (Cassis, Goertz), Alberta Agriculture and Forestry, Edmonton, Alberta; School of Public Health, University of Alberta, Edmonton, Alberta T6G 2G7 (Otto); Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta (Ponich, Checkley).

出版信息

Can Vet J. 2018 Nov;59(11):1195-1201.

PMID:30410176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6190149/
Abstract

The objectives of this study were to describe the antimicrobial susceptibility and serotypes of clinical spp. isolates from Alberta cattle, to inform antimicrobial stewardship decisions for Alberta bovine veterinarians and to provide data for national surveillance. Isolates were collected from cattle and serotyped by Alberta Agriculture and Forestry from 2006 to 2014. Susceptibility testing was completed using Canadian surveillance breakpoints. There were 81 unique isolates from 72 visits to 27 farms. The majority of isolates were Typhimurium (66.7%) and Dublin (19.8%). The prevalence of multidrug resistance was high in Typhimurium (89.1%) and Dublin (93.8%), including ceftiofur resistance (43.6% and 68.8%, respectively), while there was no resistance in other serotypes. As ceftiofur is a recommended treatment option for enteritis and septicemia caused by in cattle, these results reinforce that obtaining bacterial culture and susceptibility results is critical for suspected cases of bovine salmonellosis in Alberta.

摘要

本研究的目的是描述从艾伯塔省牛群中分离出的临床菌株的抗菌药敏性和血清型,为艾伯塔省牛兽医的抗菌药物管理决策提供信息,并为国家监测提供数据。2006年至2014年期间,艾伯塔省农业和林业部门从牛群中采集了分离株并进行血清分型。药敏试验使用加拿大监测断点标准完成。从27个农场的72次走访中分离出81株独特的菌株。大多数分离株为鼠伤寒沙门氏菌(66.7%)和都柏林沙门氏菌(19.8%)。鼠伤寒沙门氏菌(89.1%)和都柏林沙门氏菌(93.8%)的多重耐药率很高,包括头孢噻呋耐药(分别为43.6%和68.8%),而其他血清型则无耐药情况。由于头孢噻呋是牛由[此处原文可能有误,推测是指某些特定细菌]引起的肠炎和败血症的推荐治疗选择,这些结果强化了在艾伯塔省,对于疑似牛沙门氏菌病病例,获取细菌培养和药敏结果至关重要。

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本文引用的文献

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Antimicrobial usage and resistance in beef production.牛肉生产中的抗菌药物使用与耐药性
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Effects of antimicrobial use in agricultural animals on drug-resistant foodborne salmonellosis in humans: A systematic literature review.抗菌剂在农业动物中的使用对人类食源性耐药性沙门氏菌病的影响:系统文献综述。
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