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慢性肾脏病中与肢端骨质溶解相关的短指(趾)畸形:指(趾)骨形状如何影响指甲形态。

Brachyonychia Associated with Acroosteolysis in Chronic Kidney Disease: How Phalange Shape Influences Nail Morphology.

作者信息

Rosales Figueroa José David, Chang Patricia

机构信息

Centro Clínico Reforma, Ciudad de Guatemala, Guatemala.

Hospital General de Enfermedades IGSS, Ciudad de Guatemala, Guatemala.

出版信息

Skin Appendage Disord. 2018 Oct;4(4):264-267. doi: 10.1159/000487898. Epub 2018 Apr 24.

DOI:10.1159/000487898
PMID:30410893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6219246/
Abstract

Brachyonychia is a rare manifestation in patients with chronic kidney disease. Longtime disease, secondary hyperparathyroidism, and hemodialysis are common conditions among those who present it. We evaluated 8 cases who presented brachyonychia in the nephrology department and compared the clinical versus the radiographic findings, and evaluated how the tissue adjusts to the underlying bone structure, giving different forms to the nails. We conclude that brachyonychia and acroosteolysis in chronic kidney disease suggest long-term disease, secondary hyperparathyroidism, and hemodialysis, besides it being a good model on how the bony structure defines the soft tissue morphology.

摘要

短指(趾)甲是慢性肾脏病患者的一种罕见表现。病程较长、继发性甲状旁腺功能亢进和血液透析是出现短指(趾)甲的患者的常见情况。我们评估了在肾病科出现短指(趾)甲的8例患者,比较了临床和影像学表现,并评估了组织如何适应潜在的骨骼结构,从而使指甲呈现出不同形态。我们得出结论,慢性肾脏病中的短指(趾)甲和肢端骨质溶解提示病程较长、继发性甲状旁腺功能亢进和血液透析,此外,它还是一个关于骨骼结构如何定义软组织形态的良好模型。

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1
Brachyonychia Associated with Acroosteolysis in Chronic Kidney Disease: How Phalange Shape Influences Nail Morphology.慢性肾脏病中与肢端骨质溶解相关的短指(趾)畸形:指(趾)骨形状如何影响指甲形态。
Skin Appendage Disord. 2018 Oct;4(4):264-267. doi: 10.1159/000487898. Epub 2018 Apr 24.
2
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[Tranverse acro-osteolysis: A rare cause of nail dystrophy].[横贯性肢端骨质溶解症:甲营养不良的罕见病因]
Ann Dermatol Venereol. 2016 Apr;143(4):284-8. doi: 10.1016/j.annder.2016.01.008. Epub 2016 Mar 2.
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Hautarzt. 1987 Feb;38(2):104-6.
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Half and Half Nails in a Healthy Person.健康人的对半甲。
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引用本文的文献

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Nail changes in acro-osteolysis: A case report and review of the literature.肢端骨质溶解症中的指甲改变:一例报告及文献综述
JAAD Case Rep. 2019 Nov 13;5(12):1033-1036. doi: 10.1016/j.jdcr.2019.09.016. eCollection 2019 Dec.

本文引用的文献

1
Bone loss in chronic kidney disease: Quantity or quality?慢性肾脏病中的骨质流失:量还是质?
Bone. 2016 Jun;87:57-70. doi: 10.1016/j.bone.2016.03.017. Epub 2016 Apr 2.
2
Cutaneuos findings in patients with predialysis chronic kidney disease.透析前慢性肾脏病患者的皮肤表现
J Eur Acad Dermatol Venereol. 2016 Sep;30(9):1609-13. doi: 10.1111/jdv.13643. Epub 2016 Mar 30.
3
[Tranverse acro-osteolysis: A rare cause of nail dystrophy].[横贯性肢端骨质溶解症:甲营养不良的罕见病因]
Ann Dermatol Venereol. 2016 Apr;143(4):284-8. doi: 10.1016/j.annder.2016.01.008. Epub 2016 Mar 2.
4
Association of Acroosteolysis With Enhanced Osteoclastogenesis and Higher Blood Levels of Vascular Endothelial Growth Factor in Systemic Sclerosis.系统性硬化症中肢端骨质溶解与破骨细胞生成增强及血管内皮生长因子血水平升高相关。
Arthritis Rheumatol. 2016 Jan;68(1):201-9. doi: 10.1002/art.39424.
5
Acroosteolysis presenting with brachyonychia following exposure to cold.暴露于寒冷后出现肢端骨溶解伴短甲。
J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2252-4. doi: 10.1111/jdv.12826. Epub 2014 Nov 10.
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[Skin lesions in chronic renal dialysis].[慢性肾透析中的皮肤病变]
J Bras Nefrol. 2014 Jan-Mar;36(1):42-7. doi: 10.5935/0101-2800.20140008.
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Acquired racquet nails: a useful sign of hyperparathyroidism.获得性球拍状指甲:甲状旁腺功能亢进的一个有用体征。
J Eur Acad Dermatol Venereol. 2014 Feb;28(2):257-9. doi: 10.1111/jdv.12187. Epub 2013 May 20.
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[Dyspnea and shortened phalanges].[呼吸困难与指骨缩短]
Rev Med Interne. 2013 Dec;34(12):785-6. doi: 10.1016/j.revmed.2013.03.328. Epub 2013 Apr 29.
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Cutaneous and nail changes in patients of chronic kidney disease: observations in a tertiary care unit from South India.慢性肾脏病患者的皮肤和指甲变化:来自印度南部一家三级医疗单位的观察结果
Hemodial Int. 2013 Jul;17(3):468-70. doi: 10.1111/hdi.12050. Epub 2013 Apr 28.
10
Various musculoskeletal manifestations of chronic renal insufficiency.慢性肾功能不全的各种骨骼肌肉表现。
Clin Radiol. 2013 Jul;68(7):e397-411. doi: 10.1016/j.crad.2013.01.025. Epub 2013 Mar 21.