Sohn Jong-Hee, Choi Yun-Ju, Kim Byung-Kun, Chung Pil-Wook, Lee Mi Ji, Chu Min Kyung, Ahn Jin-Young, Kim Byung-Su, Song Tae-Jin, Oh Kyungmi, Lee Kwang-Soo, Kim Soo-Kyoung, Park Kwang-Yeol, Chung Jae Myun, Moon Heui-Soo, Chung Chin-Sang, Cho Soo-Jin, Park Jeong-Wook
Department of Neurology, Chuncheon Sacred Heart Hospital, Chuncheon, South Korea.
Department of Neurology, Presbyterian Medical Center, Jeonju, South Korea.
Front Neurol. 2018 Oct 26;9:908. doi: 10.3389/fneur.2018.00908. eCollection 2018.
Epidemiological data of probable cluster headaches (CH) are scarce in the relevant literature. Here, we sought to assess the prevalence and clinical characteristics of probable CH in comparison with definite CH. Data used in this study were obtained from the Korean Cluster Headache Registry (KCHR), a prospective, cross-sectional, multicenter headache registry that collected data from consecutive patients diagnosed with CH. In total, 159 patients were enrolled in this study; 20 (12.6%) were diagnosed with probable CH. The most common unfulfilled criterion in patients with probable CH was the duration of attack, which was found in 40% of patients with probable CH. Among clinical characteristics, the number of autonomic symptoms tended to be lower in probable CH than in definite CH (1.7 ± 1.2 vs. 2.4 ± 1.5, = 0.051) and conjunctival injection and lacrimation showed an increased odds ratio (OR) [OR = 3.03; 95% confidence interval (CI): 1.03-8.33] in definite CH. The groups did not differ with regard to baseline demographic characteristics, disability, impact on life, or treatment response. Probable CH is relatively common among CH disorders, with a clinical impact similar to that of definite CH.
相关文献中关于可能的丛集性头痛（CH）的流行病学数据匮乏。在此，我们试图评估可能的CH与确诊的CH相比的患病率及临床特征。本研究中使用的数据来自韩国丛集性头痛登记处（KCHR），这是一个前瞻性、横断面、多中心的头痛登记处，收集了连续诊断为CH的患者的数据。本研究共纳入159例患者；20例（12.6%）被诊断为可能的CH。可能的CH患者中最常见的未满足标准是发作持续时间，40%的可能的CH患者存在该情况。在临床特征方面，可能的CH患者自主神经症状的数量往往低于确诊的CH患者（1.7±1.2 vs. 2.4±1.5，P = 0.051），而结膜充血和流泪在确诊的CH患者中显示出更高的优势比（OR）[OR = 3.03；95%置信区间（CI）：1.03 - 8.33]。两组在基线人口统计学特征、残疾情况、对生活的影响或治疗反应方面无差异。可能的CH在CH疾病中相对常见，其临床影响与确诊的CH相似。
