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使用电子健康记录数据验证一种基于索赔的算法以识别慢性血栓栓塞性肺动脉高压患者。

Validation of a claims-based algorithm to identify patients with chronic thromboembolic pulmonary hypertension using electronic health record data.

作者信息

Teal Simon, Auger William R, Hughes Rodney J, Ramey Dena Rosen, Lewis Kelly S, O'Brien Gerald, Yaldo Avin, Burton Tanya M, Bancroft Tim, Seare Jerry, Fabian Joerg

机构信息

1 Bayer AG, Berlin, Germany.

2 University of California, San Diego, LA Jolla, CA, USA.

出版信息

Pulm Circ. 2019 Jan-Mar;9(1):2045894018814772. doi: 10.1177/2045894018814772. Epub 2018 Nov 13.

DOI:10.1177/2045894018814772
PMID:30419792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6287311/
Abstract

This study aimed to validate an algorithm developed to identify chronic thromboembolic pulmonary hypertension (CTEPH) among patients with a history of pulmonary embolism. Validation was halted because too few patients had gold-standard evidence of CTEPH in the administrative claims/electronic health records database, suggesting that CTEPH is underdiagnosed.

摘要

本研究旨在验证一种针对有肺栓塞病史的患者开发的用于识别慢性血栓栓塞性肺动脉高压（CTEPH）的算法。由于在管理性索赔/电子健康记录数据库中，仅有极少患者具备CTEPH的金标准证据，因此验证工作被迫中止，这表明CTEPH存在诊断不足的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3aa/6287311/789e5378f138/10.1177_2045894018814772-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3aa/6287311/789e5378f138/10.1177_2045894018814772-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3aa/6287311/789e5378f138/10.1177_2045894018814772-fig1.jpg

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本文引用的文献

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An epidemiological analysis of the burden of chronic thromboembolic pulmonary hypertension in the USA, Europe and Japan.美国、欧洲和日本慢性血栓栓塞性肺动脉高压负担的流行病学分析。
Eur Respir Rev. 2017 Mar 29;26(143). doi: 10.1183/16000617.0121-2016. Print 2017 Mar 31.
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Diagnosis of chronic thromboembolic pulmonary hypertension.慢性血栓栓塞性肺动脉高压的诊断
Eur Respir Rev. 2017 Mar 15;26(143). doi: 10.1183/16000617.0108-2016. Print 2017 Jan.
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急性肺栓塞后慢性血栓栓塞性肺动脉高压的发生率：已发表文献的当代观点。
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Pulm Circ. 2016 Dec;6(4):472-482. doi: 10.1086/688084.
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An Update on the Management of Chronic Thromboembolic Pulmonary Hypertension.慢性血栓栓塞性肺动脉高压的管理最新进展
Curr Probl Cardiol. 2017 Jan;42(1):7-38. doi: 10.1016/j.cpcardiol.2016.11.001. Epub 2016 Nov 14.
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Monitoring for Pulmonary Hypertension Following Pulmonary Embolism: The INFORM Study.肺栓塞后肺动脉高压的监测：INFORM研究
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Blood Rev. 2014 Nov;28(6):221-6. doi: 10.1016/j.blre.2014.07.003. Epub 2014 Aug 15.
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