Alqahtani Fawaz F, Offiah Amaka C
Academic Unit of Child Health, Department of Oncology and Metabolism, Medical School, Damer Street Building, Sheffield Children's Hospital, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.
Department of Radiological Sciences, College of Applied Medical Sciences, Najran University, Najran, Kingdom of Saudi Arabia.
Pediatr Radiol. 2019 Mar;49(3):283-296. doi: 10.1007/s00247-018-4279-5. Epub 2018 Nov 12.
Osteoporosis is a generalised disorder of the skeleton with reduced bone density and abnormal bone architecture. It increases bone fragility and renders the individual susceptible to fractures. Fractures of the vertebrae are common osteoporotic fractures. Vertebral fractures may result in scoliosis or kyphosis and, because they may be clinically silent, it is imperative that vertebral fractures are diagnosed in children accurately and at an early stage, so the necessary medical care can be implemented. Traditionally, diagnosis of osteoporotic vertebral fractures has been from lateral spine radiographs; however, a small number of studies have shown that dual energy x-ray absorptiometry is comparable to radiographs for identifying vertebral fractures in children, while allowing reduced radiation exposure. The diagnosis of vertebral fractures from dual energy x-ray absorptiometry is termed vertebral fracture assessment. Existing scoring systems for vertebral fracture assessment in adults have been assessed for use in children, but there is no standardisation and observer reliability is variable. This literature review suggests the need for a semiautomated tool that (compared to the subjective and semiquantitative methods available) will allow more reliable and precise detection of vertebral fractures in children.
骨质疏松症是一种全身性骨骼疾病,其骨密度降低且骨结构异常。它会增加骨骼脆性,使个体易发生骨折。椎体骨折是常见的骨质疏松性骨折。椎体骨折可能导致脊柱侧弯或后凸,而且由于这些骨折在临床上可能没有症状,所以必须在儿童期准确、早期地诊断椎体骨折,以便实施必要的医疗护理。传统上,骨质疏松性椎体骨折的诊断依靠脊柱侧位X线片;然而,少数研究表明,双能X线吸收法在识别儿童椎体骨折方面与X线片相当,同时能减少辐射暴露。通过双能X线吸收法诊断椎体骨折被称为椎体骨折评估。现有的成人椎体骨折评估评分系统已被评估用于儿童,但尚无标准化,且观察者间的可靠性存在差异。这篇文献综述表明需要一种半自动化工具(与现有的主观和半定量方法相比),以便更可靠、精确地检测儿童椎体骨折。