Department of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Miami Miller School of Medicine, Miami, FL 33137, USA.
Jackson Memorial Pediatric Residency Program/University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Nutrients. 2018 Nov 9;10(11):1715. doi: 10.3390/nu10111715.
More than fifty percent of all new patient visits to pediatric gastroenterology clinics consult for functional abdominal pain disorders (FAPDs). In 2005, a technical report of the American Academy of Pediatrics and the North American Pediatric Gastroenterology, Hepatology and Nutrition society (NASPGHAN) found limited or inconclusive evidence for most therapeutic interventions for this group of disorders. The report did not include studies on herbs and spices. Since then, there has been an increasing interest in the use of complementary and alternative medicine (CAM) for the treatment of chronic pain disorders in children. About 40% of parents of pediatric gastroenterology patients have utilized CAM. This review evaluated the published literature on the effectiveness of CAM, specifically the use of herbs and spices, for the treatment of FAPDs. We found little evidence for most of the commonly used herbs and spices. Despite its common use, research on the efficacy, safety, and optimal dosage remains limited. There is evidence to suggest the benefit of peppermint oil and STW 5 for the treatment of FAPDs in children. The paucity of data on most therapies underscores the need for large clinical trials to assess their efficacy.
超过 50%的儿科消化内科新患者就诊是为了功能性腹痛障碍（FAPD）。2005 年，美国儿科学会和北美儿童胃肠病学、肝病学和营养学会（NASPGHAN）的一份技术报告发现，针对这组疾病的大多数治疗干预措施的证据有限或不明确。该报告未包括草药和香料的研究。此后，人们对使用补充和替代医学（CAM）治疗儿童慢性疼痛障碍越来越感兴趣。大约 40%的儿科胃肠病患者的家长曾使用过 CAM。这篇综述评估了关于 CAM（特别是草药和香料）治疗 FAPD 的有效性的已发表文献。我们发现大多数常用草药和香料的证据有限。尽管其使用广泛，但关于其疗效、安全性和最佳剂量的研究仍然有限。有证据表明薄荷油和 STW 5 对治疗儿童 FAPD 有益。大多数疗法的数据匮乏突出表明需要进行大型临床试验来评估其疗效。
