Borges Marcus Kiiti, Jacinto Alessandro Ferrari, Citero Vanessa Albuquerque
MSc, Postgraduate Program in Psychiatry, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, SP, Brazil.
PhD Associate Professor, Department of Internal Medicine, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Botucatu, SP, Brazil.
Dement Neuropsychol. 2018 Jul-Sep;12(3):235-243. doi: 10.1590/1980-57642018dn12-030003.
The ANU-ADRI is a self-report tool that assesses risk for Alzheimer's Disease (AD).
To validate an adapted Portuguese version of this instrument and to carry out the reliability Test-Retest of the ANU-ADRI in Brazil.
In this longitudinal study, the sample was formed (n=100) by two groups (A and B): each comprising 50 patients assisted by GPs (general practitioners) or specialists in dementia. All participants were cognitively healthy upon screening using the MMSE. The ANU-ADRI was applied at baseline (Test) and again within 1 week of the test (Retest).
There was a correlation between the mean scores of the ANU-ADRI Test and Retest (r=0.918, P<0.001). Group A had higher ANU-ADRI scores than those of group B (P<0.05). There was a moderate negative linear relation between the ANU-ADRI and MMSE scores (r= -0.353, P<0.001).
The ANU-ADRI is a valid and reliable instrument to assess whether community-dwelling Brazilians are at greater risk for AD. Low levels of education were associated with higher risk scores on the ANU-ADRI.
ANU-ADRI是一种评估阿尔茨海默病（AD）风险的自我报告工具。
验证该工具的葡萄牙语改编版本，并在巴西进行ANU-ADRI的重测信度测试。
在这项纵向研究中，样本（n = 100）由两组（A组和B组）组成：每组包括50名由全科医生（GP）或痴呆症专家诊治的患者。所有参与者在使用MMSE进行筛查时认知功能均正常。ANU-ADRI在基线时（测试）应用，并在测试后1周内再次应用（重测）。
ANU-ADRI测试和重测的平均得分之间存在相关性（r = 0.918，P < 0.001）。A组的ANU-ADRI得分高于B组（P < 0.05）。ANU-ADRI与MMSE得分之间存在中度负线性关系（r = -0.353，P < 0.001）。
ANU-ADRI是评估巴西社区居民患AD风险是否更高的有效且可靠的工具。低教育水平与ANU-ADRI上的高风险得分相关。
