Mosquera-Lopez Clara, Leitschuh Joseph, Condon John, Hagen Chad C, Hanks Cody, Jacobs Peter G
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:6044-6047. doi: 10.1109/EMBC.2018.8513602.
We present a method for automated diagnosis and classification of severity of sleep apnea using an array of non-contact pressure-sensitive sensors placed underneath a mattress as an alternative to conventional obtrusive sensors. Our algorithm comprises two stages: i) A decision tree classifier that identifies patients with sleep apnea, and ii) a subsequent linear regression model that estimates the Apnea-Hypopnea Index (AHI), which is used to determine the severity of sleep disordered breathing. We tested our algorithm on a cohort of 14 patients who underwent overnight home sleep apnea test. The machine learning algorithm was trained and performance was evaluated using leave-one-patient-out cross-validation. The accuracy of the proposed approach in detecting sleep apnea is 86.96%, with sensitivity and specificity of 81.82% and 91.67%, respectively. Moreover, classification of severity of the sleep disorder was correctly assigned in 11 out of 14 cases, and the mean absolute error in the AHI estimation was calculated to be 3.83 events/hr.
我们提出了一种使用放置在床垫下方的一系列非接触式压敏传感器自动诊断睡眠呼吸暂停并对其严重程度进行分类的方法,以此替代传统的侵入式传感器。我们的算法包括两个阶段:i)一个决策树分类器,用于识别患有睡眠呼吸暂停的患者;ii)一个后续的线性回归模型,用于估计呼吸暂停低通气指数(AHI),该指数用于确定睡眠呼吸障碍的严重程度。我们在一组接受过夜家庭睡眠呼吸暂停测试的14名患者中测试了我们的算法。使用留一法交叉验证对机器学习算法进行训练并评估其性能。所提出的方法检测睡眠呼吸暂停的准确率为86.96%,敏感性和特异性分别为81.82%和91.67%。此外,在14例病例中有11例正确分配了睡眠障碍严重程度的分类,AHI估计的平均绝对误差计算为3.83次/小时。