Martínez-Ferraté Oriol, Werlé Christophe, Franciò Giancarlo, Leitner Walter
Max Planck Institute for Chemical Energy Conversion Stiftstr. 34-36 Mülheim an der Ruhr 45470 Germany.
Institut für Technische und Makromolekulare Chemie (ITMC) RWTH Aachen University Worringer Weg 2 Aachen 52074 Germany.
ChemCatChem. 2018 Oct 23;10(20):4514-4518. doi: 10.1002/cctc.201800953. Epub 2018 Oct 11.
A catalytic system based on complexes comprising abundant and cheap manganese together with readily available aminotriazole ligands is reported. The new Mn(I) complexes are catalytically competent in transfer hydrogenation of ketones with 2-propanol as hydrogen source. The reaction proceeds under mild conditions at 80 °C for 20 h with 3 % of catalyst loading using either KO Bu or NaOH as base. Good to excellent yields were obtained for a wide substrate scope with broad functional group tolerance. The obtained results by varying the substitution pattern of the ligand are consistent with an out-sphere mechanism for the H-transfer.
据报道，一种基于配合物的催化体系，该配合物包含丰富且廉价的锰以及易于获得的氨基三唑配体。新型锰（I）配合物在以2-丙醇为氢源的酮的转移氢化反应中具有催化活性。该反应在温和条件下，于80 °C下进行20小时，使用叔丁醇钾或氢氧化钠作为碱，催化剂负载量为3 %。对于广泛的底物范围和宽泛的官能团耐受性，均获得了良好至优异的产率。通过改变配体的取代模式所获得的结果与氢转移的外层机理一致。
