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对比剂诱导的急性肾损伤的预防与管理:文献综述

The Prevention and Management of Contrast-induced Acute Kidney Injury: A Mini-review of the Literature.

作者信息

Ali Asad, Bhan Chandur, Malik Muhammad Bilal, Ahmad Malik Qistas, Sami Shahzad Ahmed

机构信息

Medicine, CMH Lahore Medical College and Institute of Dentistry, Lahore, PAK.

Internal Medicine, Chandka Medical College Hospital, Larkana, PAK.

出版信息

Cureus. 2018 Sep 11;10(9):e3284. doi: 10.7759/cureus.3284.

Abstract

Contrast-induced acute kidney injury, also called contrast-induced nephropathy, is one of the main causes of acute renal failure/acute kidney injury (AKI) in hospitalized patients within 48 to 72 hours of contrast media administration during various radiologic procedures. Several factors can be responsible for contrast-induced acute tubular necrosis (ATN); however, patient and procedure-related factors play the lead role in determining the development of contrast-induced nephropathy. There is no definitive treatment and hydration remains the mainstay preventive strategy. This article will review the incidence, criteria for definitive diagnosis, and an effective approach on how to prevent contrast-induced nephropathy in a clinical setup.

摘要

对比剂诱导的急性肾损伤,也称为对比剂肾病,是住院患者在进行各种放射学检查过程中,于注射对比剂后48至72小时内发生急性肾衰竭/急性肾损伤(AKI)的主要原因之一。多种因素可导致对比剂诱导的急性肾小管坏死(ATN);然而,患者及检查相关因素在决定对比剂肾病的发生中起主要作用。目前尚无确切的治疗方法,水化仍然是主要的预防策略。本文将综述对比剂肾病的发病率、确诊标准以及在临床环境中预防对比剂肾病的有效方法。

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