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辐射与男性生育力。

Radiations and male fertility.

机构信息

Department of Applied Physics, Aalto University, Espoo, Finland.

American Center for Reproductive Medicine, Cleveland Clinic, Mail Code X-11, 10681 Carnegie Avenue, Cleveland, OH, 44195, USA.

出版信息

Reprod Biol Endocrinol. 2018 Dec 9;16(1):118. doi: 10.1186/s12958-018-0431-1.

Abstract

During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat and extreme exposure to pesticides, radiations, radioactivity and other hazardous substances. We are surrounded by several types of ionizing and non-ionizing radiations and both have recognized causative effects on spermatogenesis. Since it is impossible to cover all types of radiation sources and their biological effects under a single title, this review is focusing on radiation deriving from cell phones, laptops, Wi-Fi and microwave ovens, as these are the most common sources of non-ionizing radiations, which may contribute to the cause of infertility by exploring the effect of exposure to radiofrequency radiations on the male fertility pattern. From currently available studies it is clear that radiofrequency electromagnetic fields (RF-EMF) have deleterious effects on sperm parameters (like sperm count, morphology, motility), affects the role of kinases in cellular metabolism and the endocrine system, and produces genotoxicity, genomic instability and oxidative stress. This is followed with protective measures for these radiations and future recommendations. The study concludes that the RF-EMF may induce oxidative stress with an increased level of reactive oxygen species, which may lead to infertility. This has been concluded based on available evidences from in vitro and in vivo studies suggesting that RF-EMF exposure negatively affects sperm quality.

摘要

近年来,越来越多的男性不育归因于一系列环境、健康和生活方式因素。男性不育可能受到强烈暴露于高温和极端暴露于杀虫剂、辐射、放射性物质和其他有害物质的影响。我们周围存在多种类型的电离和非电离辐射,两者都对精子发生有公认的致病作用。由于不可能在一个标题下涵盖所有类型的辐射源及其生物学效应,因此本综述重点关注来自手机、笔记本电脑、Wi-Fi 和微波炉的辐射,因为这些是非电离辐射的最常见来源,它们可能通过探索射频辐射对男性生育模式的影响而导致不育。从目前现有的研究来看,射频电磁场 (RF-EMF) 对精子参数(如精子计数、形态、活力)有有害影响,影响细胞代谢和内分泌系统中激酶的作用,并产生遗传毒性、基因组不稳定性和氧化应激。然后提出了这些辐射的防护措施和未来的建议。该研究得出的结论是,射频电磁场可能会产生氧化应激,增加活性氧的水平,从而导致不育。这是根据体外和体内研究的现有证据得出的,这些研究表明射频电磁场暴露会对精子质量产生负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aa4/6240172/7cf1e81b931c/12958_2018_431_Fig1_HTML.jpg

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