Goshorn S C, Schlievert P M
Department of Microbiology, University of Minnesota Medical School, Minneapolis 55455.
Infect Immun. 1988 Sep;56(9):2518-20. doi: 10.1128/iai.56.9.2518-2520.1988.
The nucleotide sequence of the gene speC, encoding streptococcal pyrogenic exotoxin type C (SPE C), was determined. The gene encoded a mature protein of 208 amino acids, with a calculated molecular weight of 24,354. The mature amino acid sequence of SPE C was analyzed for homology with the amino acid sequences of streptococcal pyrogenic exotoxin type A, the staphylococcal enterotoxins, and toxic shock syndrome toxin-1. Of these, SPE C shared the greatest amount of homology with streptococcal exotoxin type A.
测定了编码C型链球菌致热外毒素（SPE C）的speC基因的核苷酸序列。该基因编码一个由208个氨基酸组成的成熟蛋白，计算分子量为24354。分析了SPE C成熟氨基酸序列与A型链球菌致热外毒素、葡萄球菌肠毒素及中毒性休克综合征毒素-1氨基酸序列的同源性。其中，SPE C与A型链球菌外毒素的同源性最高。
