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单髁和全膝关节置换术后 12 个月内恢复期望活动的预测因素。

Predictors of return to desired activity 12 months following unicompartmental and total knee arthroplasty.

机构信息

a Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences , University of Oxford, Botnar Research Centre , Oxford , UK ;

b Arthritis Research UK Centre for Sport , Exercise and Osteoarthritis, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences , University of Oxford, Botnar Research Centre , Oxford , UK ;

出版信息

Acta Orthop. 2019 Feb;90(1):74-80. doi: 10.1080/17453674.2018.1542214. Epub 2018 Nov 19.

Abstract

Background and purpose - 1 in 5 patients are dissatisfied following unicompartmental or total knee arthroplasty (UKA or TKA). This may be partly explained by failing to return to desired activity post-arthroplasty. To facilitate return to desired activity, a greater understanding of predictors of return to desired activity in UKA and TKA patients is needed. We compared rates of return to desired activity 12 months following UKA vs. TKA, and identified and compared predictors of return to desired activity 12 months following UKA vs. TKA. Patients and methods - Patients were prospectively recruited from 2 hospitals prior to undergoing UKA or primary TKA. Patients reported preoperatively the activity/activities that were limited due to their knee that they wished to return to after arthroplasty. At 12-months postoperatively, patients reported whether they had returned to these activities ('return to desired activity'). Preoperative predictors evaluated were age, sex, BMI, education, comorbidities, pain expectations, Oxford Knee Score (OKS), UCLA Activity Score, and EQ-5D. Generalized linear models assessed the relationship between potential predictors and return-to-desired-activity. Results - The response rate of all patients eligible for 12-month follow-up was 74%. TKA patients (n = 575) were older (mean (SD) 70 (9) vs. 67 (10)) with a greater BMI (31 (6) vs. 30 (5)) than patients undergoing UKA (n = 420). 75% of UKA and 59% of TKA patients returned to desired activity. TKA patients had a greater risk of non-return to desired activity than patients undergoing UKA (risk ratio (95% CI) 1.5 (1.2-1.8)). Predictors of non-return to desired activity following UKA were worse OKS (0.96 (0.93-0.99)), higher BMI (1.04 (1.01-1.08)), and worse expectations (1.9 (1.2-2.8)). Predictors of non-return to desired activity following TKA were worse EQ-5D (0.53 (0.33-0.85)) and worse OKS (0.98 (0.96-1.0)). Interpretation - UKA patients were more likely to return to desired activity than TKA patients. Predictors of return to desired activity differed following UKA and TKA. Optimizing selection of arthroplasty procedure based on patient characteristics and targeting predictors of poor outcome may facilitate return to desired activity with potential to enhance postoperative satisfaction.

摘要

背景与目的——1 例接受单髁或全膝关节置换术(UKA 或 TKA)的患者中,有 5 例感到不满。这可能部分归因于术后未能恢复到期望的活动水平。为了促进恢复到期望的活动水平,需要更好地了解 UKA 和 TKA 患者恢复到期望的活动水平的预测因素。我们比较了 UKA 和 TKA 患者术后 12 个月恢复到期望的活动水平的比例,并确定和比较了 UKA 和 TKA 患者术后 12 个月恢复到期望的活动水平的预测因素。

患者和方法——患者在接受 UKA 或初次 TKA 前于 2 家医院前瞻性招募。患者术前报告了因膝关节问题而受限、术后希望恢复的活动/活动。术后 12 个月,患者报告是否已恢复这些活动(“恢复到期望的活动”)。评估的术前预测因素包括年龄、性别、BMI、教育程度、合并症、疼痛预期、牛津膝关节评分(OKS)、UCLA 活动评分和 EQ-5D。广义线性模型评估了潜在预测因素与恢复期望活动之间的关系。

结果——所有有资格进行 12 个月随访的患者的回复率为 74%。TKA 患者(n=575)年龄较大(平均值(标准差)为 70(9)岁比 67(10)岁),BMI 较高(31(6)比 30(5))。与接受 UKA 的患者(n=420)相比。75%的 UKA 和 59%的 TKA 患者恢复到期望的活动。与接受 UKA 的患者相比,接受 TKA 的患者恢复到期望的活动的风险较低(风险比(95%CI)为 1.5(1.2-1.8))。UKA 术后未恢复期望活动的预测因素为较差的 OKS(0.96(0.93-0.99))、较高的 BMI(1.04(1.01-1.08))和较差的预期(1.9(1.2-2.8))。TKA 术后未恢复期望活动的预测因素为较差的 EQ-5D(0.53(0.33-0.85))和较差的 OKS(0.98(0.96-1.0))。

结论——与 TKA 患者相比,UKA 患者更有可能恢复到期望的活动水平。UKA 和 TKA 术后恢复期望活动的预测因素不同。根据患者特征优化关节置换手术选择,并针对不良结局的预测因素进行靶向治疗,可能有助于恢复期望的活动,从而提高术后满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e79e/6366469/2c049aac0c8f/IORT_A_1542214_F0001_C.jpg

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