Division of Endocrinology, Metabolism, and Diabetes and Anschutz Health and Wellness Center, University of Colorado, School of Medicine, Aurora, CO 80045, USA.
Institut Pluridisciplinaire Hubert Curien, Université de Strasbourg, CNRS 67000 Strasbourg, France.
Int J Environ Res Public Health. 2018 Nov 16;15(11):2566. doi: 10.3390/ijerph15112566.
Office workers are vulnerable to the adverse health effects of sedentary behavior (i.e., sitting time). Increasing physical activity and preventing time spent sitting is an occupational health priority. This randomized crossover design study compared the short-term (3-days) effects of hourly interruptions of sedentary time with 5-min micrrobouts of activity for 9 hours (MICRO) to a sedentary control condition (SED) and a duration-matched continuous single bout of physical activity (45-min/d, ONE) condition on inclinometer-derived sitting-time on work and non-work days in sedentary overweight/obese adults. Differences in sitting/lying, standing, stepping, number of sit/stand transitions, time spent in moderate and vigorous activity (MVPA), energy expenditure, self-perceived vigor and fatigue, and insulin sensitivity were also examined. Twenty-two participants (10M/12F; 31.7 ± 1.3 year old BMI 30.4 ± 0.5 kg/m²) completed all conditions. No between-condition effects were observed in sitting-time and sit/stand transitions. Both interventions increased daily steps, MVPA and energy expenditure with increases being greater in ONE than MICRO. Feelings of vigor and fasting insulin sensitivity were also improved. Participants reported less fatigue with MICRO than SED and ONE. Both interventions increase physical activity and energy expenditure in occupational and leisure-time contexts. The sustainability of these effects over the long term and on health outcomes will need to be tested in future studies.
上班族容易受到久坐行为（即坐立时间）对健康的不利影响。增加身体活动量并防止久坐时间过长是职业健康的重点。本随机交叉设计研究比较了每小时中断久坐时间与 5 分钟微运动（MICRO）、9 小时久坐对照条件（SED）和与久坐对照条件时长匹配的连续单次身体活动（45 分钟/天，ONE）条件对超重/肥胖久坐成年人工作和非工作日计步器测量的久坐时间的短期（3 天）影响。还检查了坐姿/躺姿、站立、踏步、坐姿/站立转换次数、中高强度活动（MVPA）时间、能量消耗、自我感知活力和疲劳以及胰岛素敏感性的差异。22 名参与者（10 名男性/12 名女性；31.7 ± 1.3 岁，BMI 为 30.4 ± 0.5 kg/m²）完成了所有条件。在坐姿时间和坐姿/站立转换次数方面，没有观察到条件之间的差异。两种干预措施都增加了每日步数、MVPA 和能量消耗，ONE 组的增加幅度大于 MICRO 组。活力感和空腹胰岛素敏感性也有所改善。与 SED 和 ONE 相比，参与者报告 MICRO 组的疲劳感更低。两种干预措施都增加了职业和休闲时间的身体活动量和能量消耗。需要在未来的研究中测试这些效果在长期和对健康结果的可持续性。
