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基于 SCNN 和 ResNet 模型结合 SIFT-Flow 算法的肾脏及占位性病变区域的深度语义分割。

Deep Semantic Segmentation of Kidney and Space-Occupying Lesion Area Based on SCNN and ResNet Models Combined with SIFT-Flow Algorithm.

机构信息

School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, Jiangsu, China.

Changshu Affiliated Hospital of Soochow University (Changshu No.1 People's Hospital), Changshu, 215500, Jiangsu, China.

出版信息

J Med Syst. 2018 Nov 19;43(1):2. doi: 10.1007/s10916-018-1116-1.

Abstract

Renal segmentation is one of the most fundamental and challenging task in computer aided diagnosis systems. In order to overcome the shortcomings of automatic kidney segmentation based on deep network for abdominal CT images, a two-stage semantic segmentation of kidney and space-occupying lesion area based on SCNN and ResNet models combined with SIFT-flow transformation is proposed in paper, which is divided into two stages: image retrieval and semantic segmentation. To facilitate the image retrieval, a metric learning-based approach is firstly adopted to construct a deep convolutional neural network structure using SCNN and ResNet network to extract image features and minimize the impact of interference factors on features, so as to obtain the ability to represent the abdominal CT scan image with the same angle under different imaging conditions. And then, SIFT Flow transformation is introduced, which adopts MRF to fuse label information, priori spatial information and smoothing information to establish the dense matching relationship of pixels so that the semantics can be transferred from the known image to the target image so as to obtain the semantic segmentation result of kidney and space-occupying lesion area. In order to validate effectiveness and efficiency of our proposed method, we conduct experiments on self-establish CT dataset, focus on kidney organ and most of which have tumors inside of the kidney, and abnormal deformed shape of kidney. The experimental results qualitatively and quantitatively show that the accuracy of kidney segmentation is greatly improved, and the key information of the proportioned tumor occupying a small area of the image are exhibited a good segmentation results. In addition, our algorithm has also achieved ideal results in the clinical verification, which is suitable for intelligent medicine equipment applications.

摘要

肾脏分割是计算机辅助诊断系统中最基本和最具挑战性的任务之一。为了克服基于深度网络的自动肾脏分割在腹部 CT 图像中的不足,本文提出了一种基于 SCNN 和 ResNet 模型结合 SIFT-flow 变换的两阶段肾脏和占位病变区域语义分割方法,该方法分为两个阶段:图像检索和语义分割。为了便于图像检索,首先采用基于度量学习的方法,使用 SCNN 和 ResNet 网络构建一个深度卷积神经网络结构,提取图像特征,并最小化干扰因素对特征的影响,从而获得在不同成像条件下代表相同角度的腹部 CT 扫描图像的能力。然后,引入 SIFT Flow 变换,采用 MRF 融合标签信息、先验空间信息和平滑信息,建立像素的密集匹配关系,从而将语义从已知图像转移到目标图像,得到肾脏和占位病变区域的语义分割结果。为了验证我们提出的方法的有效性和效率,我们在自建的 CT 数据集上进行了实验,该数据集主要关注肾脏器官,其中大多数肾脏内部有肿瘤,肾脏形状异常变形。实验结果从定性和定量两方面表明,肾脏分割的准确性得到了很大的提高,并且图像中比例较小的占位病变的关键信息得到了很好的分割结果。此外,我们的算法在临床验证中也取得了理想的效果,适用于智能医疗设备的应用。

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