Emerg Infect Dis. 2018 Dec;24(12):2382-2386. doi: 10.3201/eid2412.180567.
We report a disseminated infection caused by Spiroplasma apis, a honeybee pathogen, in a patient in France who had X-linked agammaglobulinemia. Identification was challenging because initial bacterial cultures and direct examination by Gram staining were negative. Unexplained sepsis in patients with agammaglobulinemia warrants specific investigation to identify fastidious bacteria such as Spiroplasma spp.
我们报告了一例由 Spiroplasma apis（一种蜜蜂病原体）引起的播散性感染，该患者为法国的一名 X 连锁无丙种球蛋白血症患者。由于最初的细菌培养和革兰氏染色直接检查均为阴性，因此鉴定具有挑战性。患有无丙种球蛋白血症的患者出现不明原因的败血症时，需要进行特定的检查以确定是否存在苛养菌，如 Spiroplasma spp。
