Key Laboratory of Bio-Resources and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Int J Mol Sci. 2018 Nov 19;19(11):3643. doi: 10.3390/ijms19113643.
The plant hormone abscisic acid (ABA) play essential roles in numerous physiological processes such as seed dormancy, seed germination, seeding growth and responses to biotic and abiotic stresses. Such biological processes are tightly controlled by a complicated regulatory network including ABA homoeostasis, signal transduction as well as cross-talking among other signaling pathways. It is known that ABA homoeostasis modulated by its production, inactivation, and transport pathways is considered to be of great importance for plant development and stress responses. Most of the enzymes and transporters involved in ABA homoeostasis have been largely characterized and they all work synergistically to maintain ABA level in plants. Increasing evidence have suggested that transcriptional regulation of the genes involved in either ABA production or ABA inactivation plays vital roles in ABA homoeostasis. In addition to transcription factors, such progress is also regulated by microRNAs and newly characterized root to shoot mobile peptide-receptor like kinase (RLKs) mediated long-distance signal transduction. Thus, ABA contents are always kept in a dynamic balance. In this review, we survey recent research on ABA production, inactivation and transport pathways, and summarize some latest findings about the mechanisms that regulate ABA homoeostasis.
植物激素脱落酸（ABA）在许多生理过程中发挥着重要作用，如种子休眠、种子萌发、种子生长以及对生物和非生物胁迫的响应。这些生物学过程受到一个复杂的调控网络的严格控制，包括 ABA 稳态、信号转导以及其他信号通路之间的串扰。已知 ABA 稳态的调节通过其产生、失活和运输途径被认为对植物发育和应激反应非常重要。涉及 ABA 稳态的大多数酶和转运蛋白已被广泛描述，它们协同工作以维持植物中的 ABA 水平。越来越多的证据表明，参与 ABA 产生或 ABA 失活的基因的转录调控在 ABA 稳态中起着至关重要的作用。除了转录因子外，这种进展还受到 microRNAs 和新鉴定的根到茎的移动肽受体样激酶（RLKs）介导的长距离信号转导的调节。因此，ABA 含量始终保持动态平衡。在这篇综述中，我们调查了 ABA 产生、失活和运输途径的最新研究，并总结了一些关于调节 ABA 稳态的机制的最新发现。
