State Key Laboratory of Crop Biology, College of Life Science, Shandong Agricultural University, Tai'an 271018, China.
Co-Innovation Center for Sustainable Forestry in Southern China & Key Laboratory of National Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, College of Biology and the Environment, Nanjing Forestry University, Nanjing 210037, China.
Int J Mol Sci. 2022 Mar 30;23(7):3796. doi: 10.3390/ijms23073796.
Alternative splicing (AS) exists in eukaryotes to increase the complexity and adaptability of systems under biophysiological conditions by increasing transcriptional and protein diversity. As a classic hormone, abscisic acid (ABA) can effectively control plant growth, improve stress resistance, and promote dormancy. At the transcriptional level, ABA helps plants respond to the outside world by regulating transcription factors through signal transduction pathways to regulate gene expression. However, at the post-transcriptional level, the mechanism by which ABA can regulate plant biological processes by mediating alternative splicing is not well understood. Therefore, this paper briefly introduces the mechanism of ABA-induced alternative splicing and the role of ABA mediating AS in plant response to the environment and its own growth.
可变剪接（AS）存在于真核生物中，通过增加转录和蛋白质的多样性，在生物物理条件下增加系统的复杂性和适应性。作为一种经典的激素，脱落酸（ABA）可以有效地控制植物的生长，提高抗逆性，促进休眠。在转录水平上，ABA 通过信号转导途径调节转录因子来帮助植物对外界环境做出反应，从而调节基因表达。然而，在后转录水平上，ABA 通过调节可变剪接来调节植物生物过程的机制尚不清楚。因此，本文简要介绍了 ABA 诱导的可变剪接的机制以及 ABA 在植物对环境及其自身生长的响应中调节 AS 的作用。
